Evidence map›Paper›PMID 38716818›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024

Long-term exposure to air pollution and road traffic noise and incidence of dementia in the Danish Nurse Cohort.

Stéphane Tuffier, Jiawei Zhang, Marie Bergmann, Rina So, George Maria Napolitano, Thomas Cole-Hunter, Matija Maric, Sonja Antic, Jørgen Brandt, Matthias Ketzel and 3 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Genetic and environmental risk factors for dementia in African adults: A systematic review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Pooled it
  3. Associations of long-term exposure to source-specific PMEuropean archives of psychiatry and clinical neuroscience · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Impact of Residential Noise Exposure on Neurological Health: A Systematic Scoping Review.Journal of urban health : bulletin of the New York Academy of Medicine · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Long-term exposure to air pollution and road traffic noise and incidence of dementia in the Danish Nurse Cohort.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stéphane TuffierSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-1969-2070
Jiawei ZhangSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-0779-6908
Marie BergmannSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-5743-5564
Rina SoSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-2113-3887
George Maria NapolitanoSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-1197-2599
Thomas Cole-HunterSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-6827-6084
Matija MaricSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Sonja AnticDepartment of Neurology, Aarhus University Hospital, Aarhus, Denmark.
Jørgen BrandtDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.ORCID 0000-0002-7580-9547
Matthias KetzelDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.ORCID 0000-0001-9519-1935
Steffen LoftSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-9552-8518
Youn-Hee LimSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Zorana Jovanovic AndersenSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-4138-9828

Funding

Novo Nordisk Foundation Challenge Programme NNF17OC0027812
6 · The paper itself

Abstract

introductionWe examined the association of long-term exposure to air pollution and road traffic noise with dementia incidence in the Danish Nurse Cohort.

methodsFemale nurses were followed for dementia incidence (hospital contact or medication prescription) from 1993/1999 to 2020. Air pollution and road traffic noise levels were estimated at nurses' residences, and their associations with dementia were examined using Cox regression models.

resultsOf 25,233 nurses 1409 developed dementia. Particulate matter with a diameter of ≤2.5 µm (PM DISCUSSION: Long-term exposure to air pollution increases risk of dementia, and physical activity may moderate this risk. HIGHLIGHTS: Long-term exposure to air pollution was associated with increased risk of dementia among female nurses from the Danish Nurse Cohort. Association of air pollution with dementia was independent of road traffic noise. Association of road traffic noise with dementia diminished after adjusting for air pollution. Physical activity moderated adverse effects of air pollution on dementia.

Indexed as

Air PollutionDementiaEnvironmental ExposureNoise, TransportationNursesParticulate MatterAdultAgedCohort StudiesDenmarkFemaleHumansIncidenceMiddle AgedRisk FactorsParticulate Matterair pollutioncohort studiesdementiaEuropeincidencenoise transportationnursesphysical activitywomen

Identifiers

PMID38716818
PMCPMC11180848

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.