Evidence map›Paper›PMID 38716791›Full record

ArticleInfluenza and other respiratory viruses2024

Estimated Impact of Nirsevimab on the Incidence of Respiratory Syncytial Virus Infections Requiring Hospital Admission in Children < 1 Year, Weeks 40, 2023, to 8, 2024, Spain.

Clara Mazagatos, Jacobo Mendioroz, Mercedes Belén Rumayor, Virtudes Gallardo García, Virginia Álvarez Río, Ana Delia Cebollada Gracia, Noa Batalla Rebollo, María Isabel Barranco Boada, Olaia Pérez-Martínez, Ana Sofía Lameiras Azevedo and 9 more

Erratum issuedAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  15. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
    Article
  16. Nirsevimab to reduce infant morbidity from respiratory syncytial virus.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Clara MazagatosNational Centre of Epidemiology, Institute of Health Carlos III, Madrid, Spain.ORCID 0000-0002-6909-6923
Jacobo MendiorozSub-direcció General de Vigilància i Resposta a Emergències de Salut Pública, Departament de Salut, Generalitat de Catalunya, Barcelona, Spain.
Mercedes Belén RumayorÁrea de Enfermedades Transmisibles, Subdirección General de Vigilancia en Salud Pública, Madrid, Spain.
Virtudes Gallardo GarcíaServicio de Vigilancia y Salud Laboral, Dirección General de Salud Pública y Ordenación Farmacéutica, Consejería de Salud y Consumo, Andalucía, Spain.
Virginia Álvarez RíoServicio de Epidemiología, Consejería de Sanidad, Dirección General de Salud Pública, Junta de Castilla y León, Valladolid, Spain.
Ana Delia Cebollada GraciaSección de Vigilancia Epidemiológica, Dirección General de Salud Pública, Zaragoza, Aragón, Spain.
Noa Batalla RebolloSubdirección de Epidemiología de la Dirección General de Salud Pública, Servicio Extremeño de Salud, Mérida, Spain.
María Isabel Barranco BoadaServicio de Epidemiología (Sección Vigilancia Epidemiológica), Consejería de Salud-Región de Murcia, Murcia, Spain.
Olaia Pérez-MartínezServizo de Epidemioloxía, Dirección Xeral de Saúde Pública, Consellería de Sanidade, Xunta de Galicia, Santiago, Spain.
Ana Sofía Lameiras AzevedoSubdirecció General d'Epidemiologia i Vigilància de la Salut, Direcció General de Salut Pública, Generalitat Valenciana, Valencia, Spain.ORCID 0000-0001-6692-5944
Nieves López González-CoviellaServicio de Epidemiología de la Dirección General de Salud Pública, Servicio Canario de la Salud, Tenerife, Spain.
Daniel CastrillejoVigilancia Epidemiológica, Consejería de Políticas Sociales y Salud Pública de Melilla, Dirección General de Salud Pública, Melilla, Spain.
Ana Fernández IbáñezDirección General de Salud Pública y Atención a la Salud Mental, Consejería de Sanidad, Principado de Asturias, Oviedo, Spain.
Jaume Giménez DuranServicio de Epidemiología, Consellería de Salut, Gobierno de las Islas Baleares, Palma, Spain.
Cristina Ramírez CórcolesSección de Epidemiología, Delegación Provincial de Sanidad de Albacete, Albacete, Spain.
Violeta Ramos MarínServicio de Epidemiología, Consejería de Sanidad y Servicios Sociales de Ceuta, Ceuta, Spain.
Amparo LarrauriNational Centre of Epidemiology, Institute of Health Carlos III, Madrid, Spain.ORCID 0000-0002-1704-2245
Susana MongeNational Centre of Epidemiology, Institute of Health Carlos III, Madrid, Spain.
SARI Sentinel Surveillance RSV Study Group

Funding

ECDC ECDC.11236.2021ECDC ECDC/2021/016
6 · The paper itself

Abstract

backgroundData from the sentinel surveillance system of severe acute respiratory infections in Spain were used to estimate the impact of administration of nirsevimab to children born from 1 April 2023 onwards.

methodsEstimated RSV hospitalisations in < 1-year-olds during weeks 40, 2023, to 8, 2024, were compared to the number that would be expected after accounting for the background change in RSV circulation in the 2023/24 season, compared to 2022/23.

resultsWe estimated 9364-9875 RSV hospitalisations less than expected, corresponding to a 74%-75% reduction.

Indexed as

Antiviral AgentsHospitalizationRespiratory Syncytial Virus InfectionsAntibodies, Monoclonal, HumanizedFemaleHumansIncidenceInfantInfant, NewbornMaleRespiratory Syncytial Virus, HumanSentinel SurveillanceSpainAntibodies, Monoclonal, HumanizedAntiviral Agentsburdenimpactrespiratory infectionsrespiratory syncitial virusSARIsurveillance

Identifiers

PMID38716791
PMCPMC11077568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.