Evidence map›Paper›PMID 38716548›Full record

ArticleCombinatorial chemistry & high throughput screening2025

Potential Molecular Markers for Cholecystic Inflammation-Induced Carcinogenesis Based on RNA-Seq Gene Screening.

Henghai Yu, Peng Chen, Ying Hu, Feng Liu, Xiaoping Wei, Mingdao Hu

Abstract read
PubMed Publisher
In one paragraph

Article in Combinatorial chemistry & high throughput screening, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Henghai YuDepartment of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical University, Yunnan, 650101, China.ORCID 0000-0002-7235-5404
Peng ChenDepartment of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical University, Yunnan, 650101, China.
Ying HuClinical Laboratory of the Second Affiliated Hospital of Kunming Medical University, Yunnan, 650032, China.
Feng LiuDepartment of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical University, Yunnan, 650101, China.
Xiaoping WeiDepartment of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical University, Yunnan, 650101, China.
Mingdao HuDepartment of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Kunming Medical University, Yunnan, 650101, China.ORCID 0000-0001-5438-4837

Funding

Yunnan Health Training Project of High-Level Talents D-2018041Yunnan Provincial Department of Education Scientific Research Fund 2022J0218Yunnan Provincial Department of Science and Technology Fund 202301AY070001-261
6 · The paper itself

Abstract

backgroundUncontrolled inflammation plays an important role in the initiation and progression of tumors. The repeated circulation and continuous stimulation of gallbladder epithelium caused by gallstones is an important risk factor for gallbladder cancer.

methodsTo study pathogenesis, samples were collected for chronic cholecystitis caused by gallstones and early and advanced gallbladder cancer with gallstones and subjected to RNA-seq analysis. Gene Ontology and Kyoto Gene and Genome Encyclopedia analyses were used to elucidate the protein-protein interaction network and identify differentially expressed genes.

resultsNine potential molecular markers,

conclusionThe potential molecular markers

Indexed as

Biomarkers, TumorCarcinogenesisCholecystitisGallbladder NeoplasmsInflammationRNA-SeqFemaleHumansMaleMiddle AgedBiomarkers, Tumorcholecystitis.Gallbladder cancerinflammation-induced carcinogenesismolecular markerRNA sequencinguncontrolled inflammation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.