Evidence map›Paper›PMID 38716192›Full record

ArticleFrontiers in cellular and infection microbiology2024

Detection of novel

Olusola Ajibaye, Yetunde Adeola Olukosi, Eniyou C Oriero, Mary Aigbiremo Oboh, Bamidele Iwalokun, Ikechukwu Chidiebere Nwankwo, Chinaza Favour Nnam, Olawunmi Victoria Adaramoye, Somadina Chukwemeka, Judith Okanazu and 3 more

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Olusola AjibayeMalaria Genomics Research and Training Centre, Department of Biochemistry & Nutrition, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Yetunde Adeola OlukosiMalaria Genomics Research and Training Centre, Department of Biochemistry & Nutrition, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Eniyou C OrieroMedical Research Council Unit, the Gambia - The London School of Hygiene and Tropical Medicine, Fajara, Banjul, Gambia.
Mary Aigbiremo ObohMedical Research Council Unit, the Gambia - The London School of Hygiene and Tropical Medicine, Fajara, Banjul, Gambia.
Bamidele IwalokunMalaria Genomics Research and Training Centre, Department of Biochemistry & Nutrition, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Ikechukwu Chidiebere NwankwoCenter for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.
Chinaza Favour NnamMalaria Genomics Research and Training Centre, Department of Biochemistry & Nutrition, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Olawunmi Victoria AdaramoyeDepartment of Obstetrics and Gynaecology, Lagos University Teaching Hospital, Idi-araba, Surulere, Lagos, Nigeria.
Somadina ChukwemekaMalaria Genomics Research and Training Centre, Department of Biochemistry & Nutrition, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Judith OkanazuMalaria Genomics Research and Training Centre, Department of Biochemistry & Nutrition, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Eniafe GabrielMalaria Genomics Research and Training Centre, Department of Biochemistry & Nutrition, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Emmanuel Oluwadare BalogunDepartment of Biochemistry, Ahmadu Bello University, Zaria, Nigeria.
Alfred Amambua-NgwaMedical Research Council Unit, the Gambia - The London School of Hygiene and Tropical Medicine, Fajara, Banjul, Gambia.

Funding

Multi-target approach to rational design of novel therapeutics for human African trypanosomiasisK43TW012015 · FIC · AHMADU BELLO UNIVERSITY · PI BALOGUN, EMMANUEL OLUWADARE · 2021 to 2025
$577k
FIC NIH HHS K43 TW012015
6 · The paper itself

Abstract

Background: Routine surveillance for antimalarial drug resistance is critical to sustaining the efficacy of artemisinin-based Combination Therapies (ACTs). Methods: Fifty-two Results: A total of 7 (26.92%) cases were identified either as early treatment failure, late parasitological failure or late clinical failure. Of the four post-treatment infections identified as recrudescence by Conclusion:

Indexed as

AntimalarialsArtemisininsDrug ResistanceMalaria, FalciparumMicrofilament ProteinsPlasmodium falciparumAdultArtemether, Lumefantrine Drug CombinationDrug CombinationsFemaleGenotypeHumansMaleMicrosatellite RepeatsMutationNigeriaAntimalarialsArtemether, Lumefantrine Drug CombinationartemisininArtemisininscoronin proteinsDrug CombinationsMicrofilament ProteinsProtozoan Proteinsartemisinin resistancecoroninlumefantrinemalariaPlasmodium falciparumpolymorphisms

Identifiers

PMID38716192
PMCPMC11074373

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.