ArticleAnalytical science advances2022
Artificial amniotic fluid for nuclear magnetic resonance spectroscopy studies.
Article in Analytical science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Neuroprotective properties of erythropoietin (Epo) and its receptor (EpoR) in open spinal dysraphism (OSD): an investigation of EpoR expression in a rat OSD model, along with in vitro studies on the neuroprotective effects of Epo on rat spinal cord-derived neural progenitor cells.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Physiological assessment of the fetal body using MRI: current uses and potential directions.The British journal of radiology · 2023Review
- Artificial amniotic fluid for nuclear magnetic resonance spectroscopy studies.Analytical science advances · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amniocentesis is the process of retrieving the nutrient-rich amniotic fluid (AF) that encompasses the growing fetus in order to diagnose fetal diseases and developmental disorders. Currently, it is only performed on pregnant persons at risk and is invasive with the potential for infection and in some cases, miscarriage. A non-invasive alternative is needed and could be developed using magnetic resonance spectroscopy (MRS). To develop such MRS sequences, ample testing and training are needed and could be most efficiently conducted on a phantom. We propose a protocol for creating such a synthetic AF phantom for MRS testing and optimization. The proposed AF is validated using nuclear magnetic resonance (NMR) proving it produces spectra comparable to those in the literature. The results from this study can aid in developing a non-invasive fetal diagnostic tool to replace amniocentesis.
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Registered trials
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