Evidence map›Paper›PMID 38716098›Full record

ArticleRSC advances2024

Curcumin-polydopamine nanoparticles alleviate ferroptosis by iron chelation and inhibition of oxidative stress damage.

Li Lei, Jiali Yuan, Qingqing Yang, Qiuxia Tu, Haijun Yu, Liangzhao Chu, Lei Tang, Chunlin Zhang

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li LeiEngineering Research Center for Molecular Medicine, School of Basic Medical Science, Guizhou Medical University Guiyang 550025 China.ORCID https://orcid.org/0000-0001-5430-9351
Jiali YuanEngineering Research Center for Molecular Medicine, School of Basic Medical Science, Guizhou Medical University Guiyang 550025 China.
Qingqing YangGuizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, College of Pharmacy, Guizhou Medical University Guiyang 550025 China.
Qiuxia TuEngineering Research Center for Molecular Medicine, School of Basic Medical Science, Guizhou Medical University Guiyang 550025 China.
Haijun YuCenter of Pharmaceutics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences Shanghai 201203 China.ORCID https://orcid.org/0000-0002-3398-0880
Liangzhao ChuDepartment of Neurosurgery, The Affiliated Hospital of Guizhou Medical University Guiyang Guizhou China.
Lei TangGuizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, College of Pharmacy, Guizhou Medical University Guiyang 550025 China.
Chunlin ZhangEngineering Research Center for Molecular Medicine, School of Basic Medical Science, Guizhou Medical University Guiyang 550025 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis, characterized by elevated iron levels and lipid peroxidation (LPO), is a recently identified regulatory mechanism of cell death. Its substantial involvement in ischemic tissue injury, neurodegenerative disorders, and cancer positions ferroptosis inhibition as a promising strategy for managing these diverse diseases. In this study, we introduce curcumin-polydopamine nanoparticles (Cur-PDA NPs) as an innovative ferroptosis inhibitor. Cur-PDA NPs demonstrate remarkable efficacy in chelating both Fe

Identifiers

PMID38716098
PMCPMC11075776

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.