Evidence map›Paper›PMID 38715838›Full record

ArticleAmerican journal of translational research2024

Early warning model for stroke recurrence in acute ischemic stroke patients based on traditional Chinese medicine syndrome theory.

Lei Li, Feng Chen, Xiaoyan Liu, Yang Yang, Jiayu Zhang, Xiaohong Zeng, Renbin Liu

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Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Lei LiDepartment of Traditional Chinese Medicine Rehabilitation, Bao'an Central Hospital of Shenzhen Shenzhen 518102, Guangdong, China.
Feng ChenDepartment of Traditional Chinese Medicine, Renmin Hospital, Hubei University of Medicine Shiyan 442000, Hubei, China.
Xiaoyan LiuHubei University of Chinese Medicine Wuhan 430056, Hubei, China.
Yang YangDepartment of Traditional Chinese Medicine Rehabilitation, Bao'an Central Hospital of Shenzhen Shenzhen 518102, Guangdong, China.
Jiayu ZhangDepartment of Traditional Chinese Medicine Rehabilitation, Bao'an Central Hospital of Shenzhen Shenzhen 518102, Guangdong, China.
Xiaohong ZengDepartment of Traditional Chinese Medicine Rehabilitation, Bao'an Central Hospital of Shenzhen Shenzhen 518102, Guangdong, China.
Renbin LiuDepartment of Traditional Chinese Medicine Rehabilitation, Bao'an Central Hospital of Shenzhen Shenzhen 518102, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to establish an early warning model for stroke recurrence in acute ischemic stroke patients based on Traditional Chinese Medicine (TCM) syndrome theory.

methodsThis retrospective study collected the data of 1741 patients with ischemic stroke from 7 clinical centers between July 2016 and November 2019. Distance correlation coefficient, mutual information entropy, and statistical correlation test were used for univariate analysis. Cox proportional hazards regression model was applied to construct and validate the stroke recurrence warning model at different time. The area under the ROC curve (AUC) was used to evaluate the early warning ability of the model.

resultsWe successfully constructed the early warning model. The median follow-up time was 1.42 years (95% CI [1.37, 1.47]). Recurrence events occurred in 175 patients, with a cumulative recurrence rate of 10.05% (95% CI [8.64, 11.47]). The AUC of the model was 0.64±0.02 in the training set and 0.70±0.03 in the validation set.

conclusionThe TCM syndrome model can give an early warning for the recurrence of stroke and provide reference for the secondary prevention of ischemic stroke.

Indexed as

early warning modelIschemic strokerecurrencerisk assessment toolstraditional Chinese medicine syndrome theory

Identifiers

PMID38715838
PMCPMC11070379

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