Evidence map›Paper›PMID 38715784›Full record

ArticleFrontiers in oncology2024

Salivary excretion of systemically injected [

Bruna Fernandes, Jyoti Roy, Falguni Basuli, Blake M Warner, Liza Lindenberg, Esther Mena, Steven S Adler, Gary L Griffiths, Peter L Choyke, Frank I Lin

Abstract read
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bruna Fernandes *Molecular Imaging Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States.
Jyoti Roy *Molecular Imaging Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States.
Falguni BasuliChemistry and Synthesis Center, National Heart, Lung and Blood Institute, Bethesda, MD, United States.
Blake M WarnerSalivary Disorders Unit, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, United States.
Liza LindenbergMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States.
Esther MenaMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States.
Steven S AdlerClinical Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Gary L GriffithsClinical Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Peter L ChoykeMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States.
Frank I LinMolecular Imaging Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States.

Funding

WORK ORDER 126643 B539 EXPAND IC SUITE75N91019D00024 · NIAID · LEIDOS BIOMEDICAL RESEARCH, INC. · PI PENDLETON, RICHARD · 2019 to 2025
$3932.6M
Growth Factor Imaging and PhotoimmunotherapyZIABC010656 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHOYKE, PETER L · 2009 to 2024
$31.6M
Instrumentation for microSPECT and microPET imagingZIABC010668 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHOYKE, PETER L · 2009 to 2025
$11.0M
Radiopharmaceutical Imaging and Therapy of CancerZIABC012167 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHOYKE, PETER L · 2024 to 2025
$3.9M
Protection of Salivary Gland in PSMA-targeted radioligand therapyZIABC011826 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LIN, FRANK · 2018 to 2025
$1.6M
Intramural NIH HHS ZIA BC011826NIH HHS 75N91019D00024
6 · The paper itself

Abstract

Introduction: Prostate-specific membrane antigen (PSMA) is present in high amounts in salivary glands, but it is unclear whether labeled binders of PSMA are excreted in the saliva. Methods: Ten patients with prostate cancer underwent whole-body [ Results: All PET scans of 10 patients (69 ± 8 years) with histologically confirmed prostate cancer (PSA= 2.4 ± 2.4, and Gleason Grade = 6-9) showed high uptake of [ Conclusion: Systemically injected [

Indexed as

[18F]-DCFPyLPET imagingPSMAsalivary excretionxerostomia

Identifiers

PMID38715784
PMCPMC11074343

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.