Evidence map›Paper›PMID 38715617›Full record

ReviewFrontiers in immunology2024

Microbiome and cancer: from mechanistic implications in disease progression and treatment to development of novel antitumoral strategies.

Marian Constantin, Mariana Carmen Chifiriuc, Grigore Mihaescu, Nicolae Corcionivoschi, Liliana Burlibasa, Coralia Bleotu, Sorin Tudorache, Magda Mihaela Mitache, Roxana Filip, Simona-Gloria Munteanu and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Molecular Mechanisms of Probiotic Action Against Gastrointestinal Cancers.International journal of molecular sciences · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marian ConstantinInstitute of Biology, Bucharest of Romanian Academy, Bucharest, Romania.
Mariana Carmen ChifiriucLife, Environmental and Earth Sciences Division, Research Institute of the University of Bucharest, Bucharest, Romania.
Grigore MihaescuFaculty of Biology, University of Bucharest, Bucharest, Romania.
Nicolae CorcionivoschiBacteriology Branch, Veterinary Sciences Division, Agri-Food and Biosciences Institute, Belfast, United Kingdom.
Liliana BurlibasaFaculty of Biology, University of Bucharest, Bucharest, Romania.
Coralia BleotuLife, Environmental and Earth Sciences Division, Research Institute of the University of Bucharest, Bucharest, Romania.
Sorin TudoracheFaculty of Medicine, Titu Maiorescu University, Bucharest, Romania.
Magda Mihaela MitacheFaculty of Medicine, Titu Maiorescu University, Bucharest, Romania.
Roxana FilipFaculty of Medicine and Biological Sciences, Stefan cel Mare University of Suceava, Suceava, Romania.
Simona-Gloria MunteanuCarol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Gratiela Gradisteanu PircalabioruLife, Environmental and Earth Sciences Division, Research Institute of the University of Bucharest, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a very aggressive disease and one of mankind's most important health problems, causing numerous deaths each year. Its etiology is complex, including genetic, gender-related, infectious diseases, dysbiosis, immunological imbalances, lifestyle, including dietary factors, pollution etc. Cancer patients also become immunosuppressed, frequently as side effects of chemotherapy and radiotherapy, and prone to infections, which further promote the proliferation of tumor cells. In recent decades, the role and importance of the microbiota in cancer has become a hot spot in human biology research, bringing together oncology and human microbiology. In addition to their roles in the etiology of different cancers, microorganisms interact with tumor cells and may be involved in modulating their response to treatment and in the toxicity of anti-tumor therapies. In this review, we present an update on the roles of microbiota in cancer with a focus on interference with anticancer treatments and anticancer potential.

Indexed as

Disease ProgressionNeoplasmsAnimalsAntineoplastic AgentsDysbiosisGastrointestinal MicrobiomeHumansMicrobiotaAntineoplastic Agentscancerimmunotherapymicrobiomemicrobiotaprobiotics

Identifiers

PMID38715617
PMCPMC11074409

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.