Evidence map›Paper›PMID 38715538›Full record

ArticlePhysical chemistry chemical physics : PCCP2024

Structural characterization of E22G Aβ

Natalie C Golota, Brian Michael, Edward P Saliba, Sara Linse, Robert G Griffin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physical chemistry chemical physics : PCCP, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Diamond rotors for high magic angle spinning frequencies.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natalie C GolotaDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. rgg@mit.edu.ORCID http://orcid.org/0000-0002-0922-0881
Brian MichaelDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. rgg@mit.edu.
Edward P SalibaDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. rgg@mit.edu.ORCID http://orcid.org/0000-0001-7357-0651
Sara LinseBiochemistry and Structural Biology, Department of Chemistry, Lund University, Lund, SE 22100, Sweden.ORCID http://orcid.org/0000-0001-9629-7109
Robert G GriffinDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. rgg@mit.edu.ORCID http://orcid.org/0000-0003-1589-832X

Funding

High Field DNP and EPR in Biological SystemsR01GM132997 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GRIFFIN, ROBERT GUY · 2019 to 2025
$4.6M
Solid State NMR Studies of Amyloid ProteinsR01AG058504 · NIA · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ROBERT Guy GRIFFIN · 2022 to 2026
$3.5M
Solid State NMR Studies of Amyloid ProteinsRF1AG058504 · NIA · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GRIFFIN, ROBERT GUY · 2017 to 2017
$3.1M
The Structures of hVDAC-1 and hVDAC-2 by High Frequency Magic Angle Spinning Nuclear Magnetic Resonance SpectroscopyF32GM139304 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SALIBA, EDWARD PAUL · 2020 to 2022
$198k
NIA NIH HHS R01 AG058504NIA NIH HHS RF1 AG058504NIGMS NIH HHS F32 GM139304NIGMS NIH HHS R01 GM132997
6 · The paper itself

Abstract

Amyloid fibrils have been implicated in the pathogenesis of several neurodegenerative diseases, the most prevalent example being Alzheimer's disease (AD). Despite the prevalence of AD, relatively little is known about the structure of the associated amyloid fibrils. This has motivated our studies of fibril structures, extended here to the familial Arctic mutant of Aβ

Indexed as

Amyloid beta-PeptidesPeptide FragmentsAmyloidEscherichia coliHumansMutationNuclear Magnetic Resonance, BiomolecularAmyloidAmyloid beta-Peptidesamyloid beta-protein (1-42)Peptide Fragments

Identifiers

PMID38715538
PMCPMC11110645

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.