Evidence map›Paper›PMID 38715422›Full record

ArticleOrthopaedic surgery2024

Does Focal Kyphotic Deformity at Non-responsible Levels Affect the Outcomes of Anterior Cervical Decompression and Fusion?

Jia Liu, Jian Tan, Haotian Wang, Yixuan Tan, Junqiang Qi, Rukun Chen, Jian Huang, Chao Zhu, Junming Tan, Wen Yuan and 2 more

Abstract read
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Article in Orthopaedic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Jia LiuDepartment of Orthopedic Surgery, Spine Center, Changzheng Hospital, Naval Military Medical University (Second Military Medical University), Shanghai, People's Republic of China.ORCID https://orcid.org/0000-0002-7441-3129
Jian TanDepartment of Medical Genetics, Naval Medical University, Shanghai, People's Republic of China.
Haotian WangDepartment of Orthopedic Surgery, Spine Center, Changzheng Hospital, Naval Military Medical University (Second Military Medical University), Shanghai, People's Republic of China.
Yixuan TanDepartment of Orthopedic Surgery, Spine Center, Changzheng Hospital, Naval Military Medical University (Second Military Medical University), Shanghai, People's Republic of China.
Junqiang QiDepartment of Orthopedic Surgery, Spine Center, Changzheng Hospital, Naval Military Medical University (Second Military Medical University), Shanghai, People's Republic of China.
Rukun ChenFaculty of Medicine, University of Southampton, Southampton, UK.
Jian HuangDepartment of Orthopedic Surgery, Spine Center, Changzheng Hospital, Naval Military Medical University (Second Military Medical University), Shanghai, People's Republic of China.
Chao ZhuDepartment of Nephrology and Rheumatology, The Third Affiliated Hospital of Naval Medical University, Shanghai, People's Republic of China.
Junming TanDepartment of Orthopedics, The 72nd Army Hospital of the People's Liberation Army, Huzhou, People's Republic of China.
Wen YuanDepartment of Orthopedic Surgery, Spine Center, Changzheng Hospital, Naval Military Medical University (Second Military Medical University), Shanghai, People's Republic of China.
Changgui ShiDepartment of Orthopedic Surgery, Spine Center, Changzheng Hospital, Naval Military Medical University (Second Military Medical University), Shanghai, People's Republic of China.ORCID https://orcid.org/0000-0002-3609-928X
Guohua XuDepartment of Orthopedic Surgery, Spine Center, Changzheng Hospital, Naval Military Medical University (Second Military Medical University), Shanghai, People's Republic of China.ORCID https://orcid.org/0000-0001-6743-1698

Funding

Shanghai Shenkang Hospital Development Center Clinical Science and Technology Innovation Project SHDC22020211The Second Affiliated Hospital of Second Military Medical University Project 2020YLCYJ-Z05
6 · The paper itself

Abstract

objectiveFocal cervical kyphotic deformity (FCK) without neurologic compression is not uncommon in patients with cervical spondylotic myelopathy (CSM) who underwent anterior cervical decompression and fusion (ACDF) surgery. It remains unclear whether FCK at non-responsible levels needs to be treated simultaneously. This study aims to investigate whether FCK at non-responsible levels is the prognostic factor for CSM and elucidate the surgical indication for FCK.

methodsPatients with CSM who underwent ACDF between January 2016 and April 2021 were included. Patients were divided into two groups according to the presence of FCK and two classifications according to global cervical sagittal alignment. Clinical outcomes were compared using Japanese Orthopaedic Association (JOA) scores and recovery rate (RR) of neurologic function. Univariate and multivariate analysis based on RR assessed the relationship between various possible prognostic factors and clinical outcomes. The receiver operating characteristic curve (ROC) was used to determine the optimal cutoff value of the focal Cobb angle to predict poor clinical outcomes.

resultsA total of 94 patients were included, 41 with FCK and 53 without. Overall, the RR of neurologic function was significantly lower in the FCK than in the non-FCK group. Further analysis showed that the RR difference between the two groups was only observed in hypo-lordosis classification (kyphotic and sigmoid alignment), but not in the lordosis classification. Multivariate analysis showed that the preoperative focal Cobb angle in the FCK level (OR = 0.42; 95% CI = 0.18-0.97) was independently associated with clinical outcomes in the hypo-lordosis classification. The optimal cutoff point of the preoperative focal kyphotic Cobb angle was calculated at 4.05°.

conclusionFor CSM with hypo-lordosis, FCK was a risk factor for poor postoperative outcomes. Surgeons may consider treating the FCK simultaneously if the focal kyphotic Cobb angle of FCK is greater than 4.05° and is accompanied by cervical global kyphotic or sigmoid deformity.

Indexed as

Cervical VertebraeDecompression, SurgicalKyphosisSpinal FusionAgedFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesSpondylosisAnterior Decompression and FusionCervical AlignmentCervical MyelopathyFocal Kyphosis

Identifiers

PMID38715422
PMCPMC11144497

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