ReviewNMR in biomedicine2024
Diffusion magnetic resonance imaging of cerebrospinal fluid dynamics: Current techniques and future advancements.
Review in NMR in biomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Glymphatic Pathway Dysfunction in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis Using Diffusion Tensor Imaging Along the Perivascular Space.CNS neuroscience & therapeutics · 2025Pooled it
- High-Resolution IVIM MRI Characterizes Diffusion-Perfusion Properties of the Parasagittal Dura.NMR in biomedicine · 2026Article
- Simultaneous Assessment of Intracranial Artery and Paravascular CSF Pulsation Using 3D Whole-Brain Diffusion-Prepared Cine bSSFP (DECAF) MRI.Magnetic resonance in medicine · 2026Article
- Robust MR-AIV: A Systematic Study of Robustness Improvement and Sensitivity Analysis of MR-AIV.bioRxiv : the preprint server for biology · 2026Article
- Brain protein burden is related to intravoxel incoherent motion: PET-MR imaging study.Frontiers in neuroscience · 2026Article
- Dynamic DWI detects respiratory modulation of brain parenchymal hydrodynamics.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- A theoretical interpretation of diffusion weighted and intravoxel incoherent motion imaging for cerebrospinal fluid flow.Magnetic resonance in medicine · 2026Article
- Bridging pathologies: Mechanistic insights into the diabetes-Alzheimer's nexus.EXCLI journal · 2026Review
- Exploratory assessment of cerebrospinal fluid-related microdynamics after mild traumatic brain injury using intravoxel incoherent motion magnetic resonance imaging.Frontiers in neuroscience · 2026Article
- Measuring CSF net velocity in the human subarachnoid space with 7T MRI: testing the classical view of CSF absorption.Fluids and barriers of the CNS · 2025Article
- Synchronous quantification of arterial, venous, and cerebrospinal fluid flow dynamics using real-time phase-contrast MRI.Fluids and barriers of the CNS · 2025Article
- A systematic review and meta-analysis on glymphatic flow dysfunction in Parkinson's disease and Parkinsonism spectrum.NPJ Parkinson's disease · 2025Article
- Human deep sleep facilitates cerebrospinal fluid dynamics linked to spontaneous brain oscillations and neural events.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Relaxation-Selective Intravoxel Incoherent Motion Imaging of Microvascular Perfusion and Fluid Compartments in the Human Choroid Plexus.NMR in biomedicine · 2025Article
- Periventricular diffusivity reflects APOE ε4-modulated amyloid accumulation and cognitive impairment in the Alzheimer's disease continuum.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Interrater and intrarater reliability of aqueduct CSF flow parameters measured by phase-contrast MRI in healthy adults.Quantitative imaging in medicine and surgery · 2025Article
- Congenital external hydrocephalus: A rare presentation of lobar holoprosencephaly in a neonate.Radiology case reports · 2025Article
- Assessing the feasibility of a new approach to measure the full spectrum of cerebrospinal fluid dynamics within the human brain using MRI: insights from a simulation study.Interface focus · 2025Article
- The pulsing brain: state of the art and an interdisciplinary perspective.Interface focus · 2025Review
- Cerebrospinal fluid flow within ventricles and subarachnoid space evaluated by velocity selective spin labeling MRI.NeuroImage · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Cerebrospinal fluid (CSF) plays a critical role in metabolic waste clearance from the brain, requiring its circulation throughout various brain pathways, including the ventricular system, subarachnoid spaces, para-arterial spaces, interstitial spaces, and para-venous spaces. The complexity of CSF circulation has posed a challenge in obtaining noninvasive measurements of CSF dynamics. The assessment of CSF dynamics throughout its various circulatory pathways is possible using diffusion magnetic resonance imaging (MRI) with optimized sensitivity to incoherent water movement across the brain. This review presents an overview of both established and emerging diffusion MRI techniques designed to measure CSF dynamics and their potential clinical applications. The discussion offers insights into the optimization of diffusion MRI acquisition parameters to enhance the sensitivity and specificity of diffusion metrics on underlying CSF dynamics. Lastly, we emphasize the importance of cautious interpretations of diffusion-based imaging, especially when differentiating between tissue- and fluid-related changes or elucidating structural versus functional alterations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.