Evidence map›Paper›PMID 38715123›Full record

ArticleBMC veterinary research2024

Battling Salmonella enteritidis infections: integrating proteomics and in vivo assessment of Galla Chinensis tannic acid.

Yuzhang Yan, Xiaohong Zheng, Xueqin Wu, Ling Wang, Jiongjie He, Baocheng Hao, Tingjun Hu, Shengyi Wang, Dongan Cui

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuzhang Yan *Key Laboratory of New Animal Drug Project, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agriculture Sciences, No. 335, Jiangouyan Street, Qilihe District, Lanzhou, Gansu Province, 730050, P.R. China.
Xiaohong Zheng *Key Laboratory of New Animal Drug Project, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agriculture Sciences, No. 335, Jiangouyan Street, Qilihe District, Lanzhou, Gansu Province, 730050, P.R. China.
Xueqin WuKey Laboratory of New Animal Drug Project, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agriculture Sciences, No. 335, Jiangouyan Street, Qilihe District, Lanzhou, Gansu Province, 730050, P.R. China.
Ling WangKey Laboratory of New Animal Drug Project, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agriculture Sciences, No. 335, Jiangouyan Street, Qilihe District, Lanzhou, Gansu Province, 730050, P.R. China.
Jiongjie HeKey Laboratory of New Animal Drug Project, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agriculture Sciences, No. 335, Jiangouyan Street, Qilihe District, Lanzhou, Gansu Province, 730050, P.R. China.
Baocheng HaoKey Laboratory of New Animal Drug Project, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agriculture Sciences, No. 335, Jiangouyan Street, Qilihe District, Lanzhou, Gansu Province, 730050, P.R. China.
Tingjun HuCollege of Animal Science and Technology, Guangxi University, Nanning, 530005, China.
Shengyi WangKey Laboratory of New Animal Drug Project, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agriculture Sciences, No. 335, Jiangouyan Street, Qilihe District, Lanzhou, Gansu Province, 730050, P.R. China. wangshengyi@caas.cn.
Dongan CuiKey Laboratory of New Animal Drug Project, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agriculture Sciences, No. 335, Jiangouyan Street, Qilihe District, Lanzhou, Gansu Province, 730050, P.R. China. cuidongan@caas.cn.

Funding

Basic Scientific Research Business Expenses of Central Public Welfare Scientific Research Institutes Y2022YJ14Innovation Program of Chinese Academy of Agricultural Sciences - Veterinary Natural Medicine and Antibiotic Replacement 25-LZIHPS-03National Key R&D Program of China 2022YFD1801102National Key R&D Program of China 2023YFD1800802Science and Technology Project of Lanzhou City 2022-2-61Technology Innovation Project of Hubei Province 2022BEC033
6 · The paper itself

Abstract

Salmonella infections pose a significant threat to animal and human health. Phytochemicals present a potential alternative treatment. Galla chinensis tannic acid (GCTA), a hydrolyzable polyphenolic compound, inhibits bacterial growth and demonstrates potential as an alternative or supplement to antibiotics to prevent Salmonella infections. However, little is known about the antimicrobial mechanism of GCTA against Salmonella. Here, we revealed 456 differentially expressed proteins upon GCTA treatment, impacting pathways related to DNA replication, repair, genomic stability, cell wall biogenesis, and lipid metabolism using TMT-labeled proteomic analysis. TEM analysis suggested altered bacterial morphology and structure post-treatment. A Salmonella-infected-mouse model indicated that GCTA administration improved inflammatory markers, alleviated intestinal histopathological alterations, and reduced Salmonella enterica serovar Enteritidis (S. Enteritidis) colonization in the liver and spleen of Salmonella-infected mice. The LD

Indexed as

ProteomicsSalmonella enteritidisSalmonella Infections, AnimalTanninsAnimalsAnti-Bacterial AgentsDrugs, Chinese HerbalFemaleMiceMice, Inbred BALB CPolyphenolsAnti-Bacterial AgentsDrugs, Chinese HerbalGalla chinensisPolyphenolstannic acidTanninsAntibacterial activityGalla Chinensis tannic acidProteomicsSalmonella enterica serovar Enteritidis

Identifiers

PMID38715123
PMCPMC11075308

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.