ArticleBMC ophthalmology2024
Observation of structural and vascular features of retina and choroid in myopia using ultra-widefield SS-OCTA.
Article in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Widefield optical coherence tomography angiography of fellow eyes in patients with Coats Disease.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Influence of Refraction on Widefield Retinal and Choroidal Vascular Metrics in Optical Coherence Tomography Angiography in a Caucasian Population.Translational vision science & technology · 2026Article
- Investigation of 3D choroidal components in myopic populations using ultra-widefield OCTA.Eye (London, England) · 2026Article
- Structural and microvascular changes in anisometropic amblyopia: a comparative analysis of swept-source OCTA.BMC ophthalmology · 2026Article
- Artificial intelligence assisted quantitative analysis of fundus structural and vascular alterations reveals fundus tessellation as a robust biomarker of myopia severity.Frontiers in cell and developmental biology · 2026Article
- Ultra-widefield swept-source OCT angiography assessment of choroidal changes in Chinese myopic adults.Frontiers in medicine · 2026Article
- The Relationship of Photopic and Mesopic Contrast Sensitivity to Retinal-Choroidal Structural Characteristics in Low-to-Moderate and High Myopia.Translational vision science & technology · 2025Article
- Three-dimensional choroidal parameter differences in myopic anisometropia.BMC ophthalmology · 2025Article
- Changes in choriocapillaris blood flow density and associated factors affecting axial elongation in Chinese children and adolescents with mild to moderate myopia: a cross-sectional study.BMC ophthalmology · 2025Article
- The Significance of OCTA in Studying Vessel Density and Retinal Thickness in Individuals with Myopia.Medicina (Kaunas, Lithuania) · 2025Article
- Differences in macular structure and microvasculature between high myopia and non-high myopia.Frontiers in medicine · 2025Article
- Binocular visual performance and optical quality of trifocal intraocular lens in Chinese patients with high myopic cataract.PloS one · 2025Article
- Understanding amblyopia from the perspective of neurovascular units: changes in the retina and brain.Frontiers in cell and developmental biology · 2025Review
- Role of artificial intelligence in optical coherence tomography in myopia and pathological myopia.Taiwan journal of ophthalmologyReview
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6 authors.
Funding
Abstract
backgroundTo find the relationship between the changes of retinal and choriodal structure/ vascular densities (VD) and the myopia progress.
methods126 eyes of 126 age-matched young participants were divided into three groups: Emmetropia and Low Myopia (EaLM) (33 eyes), Moderate Myopia (MM) (39 eyes), and High Myopia (HM) (54 eyes). Fundus images measuring 12 × 12 mm were captured using ultra-widefield swept-source optical coherence tomography angiography (SS-OCTA). Each image was uniformly divided into nine regions: supra-temporal (ST), temporal (T), infra-temporal (IT), superior (S), central macular area (C), inferior (I), supra-nasal (SN), nasal (N), and infra-nasal (IN). Various structural parameters, including inner retina thickness (IRT), outer retina thickness (ORT), and choroid thickness (CT), were assessed, and the VD of the superficial capillary plexus (SCP), deep capillary plexus (DCP), choriocapillaries (CC), and choroid vessels (ChdV) were quantified.
resultsCT in upper fundus exhibited a significant reduction from EaLM to MM. Additionally, ORT (ST, S. SN, C, N, IT, I, IN), CT (ST, S, SN, T, C, N, IT, I, IN) and VDs of SCP (ST, S, C, I, IN), DCP (ST, S, T, C, I) and ChdV (T, N, I, IN) were statistically diminished in EaLM compared to HM. Furthermore, IRT (N), ORT (N, IN), CT (S, SN, T, C, IT, I) and VDs of SCP (I, IN) and DCP (I) exhibited significant decreases as MM progressed towards HM. Intriguingly, there was a notable increase in the VD of CC (ST, S, T, C, N) as myopia progressed from MM to HM.
conclusionSignificant changes in retinal and choroid structure and vascular density occur as moderate myopia advances to high myopia. Efforts to curb myopia progression to this stage are essential, as the failure to do so may lead to the development of corresponding retinopathy.
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