Evidence map›Paper›PMID 38714948›Full record

ArticleBMC infectious diseases2024

Computer-aided designing of a novel multi‑epitope DNA vaccine against severe fever with thrombocytopenia syndrome virus.

Yiran Tao, Yu Zhang, Yumeng Li, Qiao Liu, Jin Zhu, Minjun Ji, Gaoqian Feng, Zhipeng Xu

Abstract read
In one paragraph

Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Multi-Epitope mRNA Vaccine TargetingBioinformatics and biology insights · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yiran TaoDepartment of Pathogen Biology, National Vaccine Innovation Platform, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, People's Republic of China.
Yu ZhangDepartment of Pathogen Biology, National Vaccine Innovation Platform, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, People's Republic of China.
Yumeng LiDepartment of Pathogen Biology, National Vaccine Innovation Platform, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, People's Republic of China.
Qiao LiuDepartment of Chronic Communicable Disease, Center for Disease Control and Prevention of Jiangsu Province, Nanjing, People's Republic of China.
Jin ZhuHuadong Medical Institute of Biotechniques, Nanjing, People's Republic of China.
Minjun JiDepartment of Pathogen Biology, National Vaccine Innovation Platform, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, People's Republic of China.
Gaoqian FengDepartment of Pathogen Biology, National Vaccine Innovation Platform, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, People's Republic of China.
Zhipeng XuDepartment of Pathogen Biology, National Vaccine Innovation Platform, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, People's Republic of China. zhipengxu@njmu.edu.cn.

Funding

Medical scientific research project of Jiangsu Provincial Health Commission Z2021004Natural Science Foundation of Jiangsu Province BK20211586Qinglan Project of Jiangsu Province of China KY101R202127
6 · The paper itself

Abstract

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne viral disease caused by the SFTS virus (Dabie bandavirus), which has become a substantial risk to public health. No specific treatment is available now, that calls for an effective vaccine. Given this, we aimed to develop a multi-epitope DNA vaccine through the help of bioinformatics. The final DNA vaccine was inserted into a special plasmid vector pVAX1, consisting of CD8

Indexed as

Epitopes, T-LymphocytePhlebovirusSevere Fever with Thrombocytopenia SyndromeVaccines, DNAViral VaccinesAnimalsComputational BiologyComputer-Aided DesignEpitopes, B-LymphocyteHumansEpitopes, B-LymphocyteEpitopes, T-LymphocyteVaccines, DNAViral VaccinesBioinformaticsCellular immune responsesDNA vaccinepVAX1Severe fever with thrombocytopenia syndrome

Identifiers

PMID38714948
PMCPMC11077804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.