Evidence map›Paper›PMID 38714632›Full record

Observational studyEating and weight disorders : EWD2024

Efficacy of multivitamin support following bariatric surgery in patients with obesity: a prospective observational study.

Alessio Basolo, Susanna Bechi Genzano, Jacopo Vitti, Guido Salvetti, Donatella Gilio, Giovanni Ceccarini, Giovanna Scartabelli, Chita Lippi, Rosario Bellini, Rudi Mancini and 11 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Eating and weight disorders : EWD, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06152965 (Functional Activity and Safety of a Food for Special Medical Purposes in Subjects Undergoing Bariatric Surgery), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06152965 completednot on this map

Functional Activity and Safety of a Food for Special Medical Purposes in Subjects Undergoing Bariatric Surgery: a Multicenter Prospective Observational Clinical Trial

TypeobservationalSponsorBioitalia srlRan2021 to 2023Enrolled20ConditionsBariatric Surgery
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Alessio BasoloObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Susanna Bechi GenzanoObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Jacopo VittiObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Guido SalvettiObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Donatella GilioObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Giovanni CeccariniObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Giovanna ScartabelliObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Chita LippiObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Rosario BelliniBariatric Surgery Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Rudi ManciniBariatric Surgery Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Simone D'ImporzanoBariatric Surgery Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Carlo MorettoBariatric Surgery Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Valentina AngeliObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Daniela TroianiObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Paola FierabracciObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Roberta JaccheriObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Alba CalderoneObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Anello M PomaDepartment of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, 56100, Pisa, Italy.
Luca ChiovatoIstituti Clinici Scientifici Maugeri IRCCS, 27100, Pavia, PV, Italy.
Giorgio SaponatiISPharm CRO, 55100, Lucca, Italy.
Ferruccio SantiniObesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy. ferruccio.santini@unipi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBariatric surgery (BS), an effective treatment for severe obesity and its comorbidities, may result in micronutrient and vitamin deficiencies. This monocentric prospective observational study aimed at evaluating the efficacy of a specifically designed vitamin/mineral formula (Bariatrifast, BIOITALIA S.r.l., Italy) for preventing and treating micronutrient deficiencies in patients submitted to BS.

methodsTwenty patients with severe obesity (mean weight and BMI: 123.5 kg (range 88-174) and 43.3 kg/m

resultsAll patients achieved a significant weight loss (mean - 34.7 ± 11.8 kg). No deficiencies of various vitamins/micronutrients were detected during the entire study period. The serum concentrations of vitamin B12, 25-OH Vitamin D and folic acid increased over the follow-up period compared with V0 (mean increase 243 ng/L, 23 µg /L, 8 µg/L, respectively). Compared to RYGB, patients who underwent sleeve gastrectomy showed higher levels of 25-OH vitamin D at V2, V3 and V4 (all p < 0.05), and higher levels of Vitamin B12 and folic acid at V4 (p < 0.05 and p < 0.005, respectively). No adverse events were reported.

conclusionFollowing VSG or RYGB, Bariatrifast administration was associated with normal values of essential micronutrients, and it was well-tolerated without evidence of gastrointestinal side effects. Clinical Trial Registration ClinicalTrials.gov, identifiers NCT06152965.

Indexed as

Bariatric SurgeryVitaminsAdultAgedDietary SupplementsFemaleHumansMaleMicronutrientsMiddle AgedObesity, MorbidProspective StudiesTreatment OutcomeWeight LossMicronutrientsVitaminsBariatric surgeryMicronutrientsMultivitamin supportObesity

Identifiers

PMID38714632
PMCPMC11076347

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.