Evidence map›Paper›PMID 38714595›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2024

Novel Providencia xianensis sp. nov.: A multidrug-resistant species identified in clinical infections.

Xu Dong, Yanghui Xiang, Peihong Yang, Shanmei Wang, Wenjuan Yan, Youhua Yuan, Shan Zhou, Ke Zhou, Jiayun Liu, Ying Zhang

Registry-linked trialAbstract read
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07204769 (Microbiological Characterization and Antibiotic Resistance Profiling of Providencia Spp,), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07204769 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Microbiological Characterization and Antibiotic Resistance Profiling of Providencia Spp,: An Emerging Pathogen Isolated From Urinary Tract Infections.

TypeobservationalSponsorAssiut UniversityRan2026 to 2027Enrolled241ConditionsUrinary Tract InfectionArmsAntibiotic sensitivity
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Draft genomes of multidrug-resistantMicrobiology resource announcements · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xu Dong *State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yanghui Xiang *State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Peihong Yang *Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Shanmei WangDepartment of Clinical Microbiology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, China.
Wenjuan YanDepartment of Clinical Microbiology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, China.
Youhua YuanDepartment of Clinical Microbiology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, China.
Shan ZhouDepartment of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Ke ZhouDepartment of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Jiayun LiuDepartment of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China. jiayun@fmmu.edu.cn.
Ying ZhangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. yzhang207@zju.edu.cn.

Funding

Jinan Microecological Biomedicine Shandong Laboratory project JNL-2022050BLeading Innovative and Entrepreneur Team Introduction Program of Zhejiang No. 2021R01012National Infectious Disease Medical Center B2022011-1
6 · The paper itself

Abstract

Providencia genus is known to harbor certain opportunistic pathogens capable of causing human infections. Here, we report two strains of multidrug-resistant bacteria initially identified as Providencia rettgeri by mass spectrometry, but genome analysis revealed their ANI (79.84-84.20%) and dDDH (21.1-25.6%) values to fall below the accepted species threshold for known Providencia species. We therefore propose that these isolates be recognized as a novel species, Providencia xianensis sp. nov. Alarmingly, both strains, isolated from locations far apart, exhibited resistance to last-resort antibiotics, indicating their possible wide distribution, underscoring the urgency for immediate attention and enhanced surveillance for this emerging multidrug-resistant pathogen.

Indexed as

Anti-Bacterial AgentsDrug Resistance, Multiple, BacterialEnterobacteriaceae InfectionsProvidenciaGenome, BacterialHumansMicrobial Sensitivity TestsPhylogenyRNA, Ribosomal, 16SAnti-Bacterial AgentsRNA, Ribosomal, 16SMultidrug resistanceNovel speciesProvidencia rettgeriProvidencia xianensis

Identifiers

PMID38714595
PMCPMC11271419

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.