Evidence map›Paper›PMID 38714518›Full record

ArticleInvestigative and clinical urology2024

Correlation between urine cytology results on the day after overnight continuous saline irrigation following transurethral resection of bladder tumor and bladder tumor recurrence.

Dae Hyun Kim, Min Sung Choi, Jae Hwi Choi, Chunwoo Lee, Seong Uk Jeh, Sung Chul Kam, Jeong Seok Hwa, Jae Seog Hyun, See Min Choi

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Article in Investigative and clinical urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Dae Hyun KimDepartment of Urology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea.ORCID 0009-0006-7062-9666
Min Sung ChoiDepartment of Urology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea.ORCID 0009-0003-7605-1824
Jae Hwi ChoiDepartment of Urology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea.ORCID 0000-0002-9305-2015
Chunwoo LeeInstitute of Health Science, Gyeongsang National University, Jinju, Korea.ORCID 0000-0002-5846-7039
Seong Uk JehDepartment of Urology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea.ORCID 0000-0002-0206-0555
Sung Chul KamInstitute of Health Science, Gyeongsang National University, Jinju, Korea.ORCID 0000-0001-5403-3623
Jeong Seok HwaDepartment of Urology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea.ORCID 0000-0003-3821-5237
Jae Seog HyunDepartment of Urology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea.ORCID 0000-0002-8820-4117
See Min ChoiDepartment of Urology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea.ORCID 0000-0002-6599-2640

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the relationship between urine cytology results after overnight continuous saline irrigation (OCSI) following transurethral resection of bladder tumor (TURBT) and bladder tumor recurrence in non-muscle invasive bladder cancer (NMIBC). MATERIALS AND

methodsA retrospective study was conducted on patients diagnosed with NMIBC between 2016 and 2020 after undergoing TURBT at our hospital. All patients received OCSI following TURBT and had urine cytology test at postoperative 1 day. Urine cytology was classified into three groups: Negative, low-grade urothelial neoplasm (LGUN)+atypical urothelial cells (AUC), and suspicious for high-grade urothelial carcinoma (SHGUC)+high-grade urothelial carcinoma (HGUC). Recurrence-free survival (RFS) in each group was compared using the Kaplan-Meier method. Univariable and multivariable Cox regression analyses were performed to evaluate independent prognostic factors.

resultsA total of 172 patients were included in this study. Based on urine cytology group (after OCSI), RFS did not reach the median value in the Negative group. In the LGUN+AUC group, the median RFS was 615.00 days. In the SHGUC+HGUC group, the median RFS was 377.00 days. In survival analysis, the Negative group had a longer RFS than the SHGUC+HGUC group (p=0.013). However, Cox regression analysis showed that SHGUC+HGUC was not an independent prognostic factor for recurrence.

conclusionsUrine cytology results after OCSI following TURBT in NMIBC were associated with bladder tumor recurrence. Specifically, SHGUC or HGUC in urine cytology after OCSI showed earlier recurrence than negative cases. However, further research is needed to accurately determine whether it is an independent prognostic factor.

Indexed as

Neoplasm Recurrence, LocalSaline SolutionTherapeutic IrrigationUrinary Bladder NeoplasmsUrineAgedCystectomyFemaleHumansMaleMiddle AgedRetrospective StudiesTime FactorsTransurethral Resection of BladderUrethraUrinalysisSaline SolutionBladder tumorCytologySaline solutionTherapeutic irrigationUrine

Identifiers

PMID38714518
PMCPMC11076798

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