Evidence map›Paper›PMID 38713619›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2024

NF-κB/RelA signaling in secretoglobin progenitors mediates plasticity and MMP-induced barrier disruption in house dust mite-induced allergic asthma.

Melissa E Skibba, Allan R Brasier

Abstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. RelA Signaling inInternational journal of molecular sciences · 2026
    Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Melissa E SkibbaSchool of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, United States.
Allan R BrasierSchool of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, United States.ORCID 0000-0002-5012-4090

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Epigenetic Mechanism Reprogramming Mucosal Anti-viral Immunity in Allergic AsthmaU01AI136994 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI BRASIER, ALLAN R., CALHOUN, WILLIAM J · 2019 to 2023
$3.4M
NCATS NIH HHS UL1 TR002373NIAID NIH HHS U01 AI136994
6 · The paper itself

Abstract

The mechanisms how aeroallergens induce sensitization are incompletely understood. The house dust mite (HDM)

Indexed as

AsthmaNF-kappa BSignal TransductionTranscription Factor RelAAllergensAnimalsEpithelial CellsMiceMice, Inbred C57BLPyroglyphidaeSecretoglobinsAllergensNF-kappa BRela protein, mouseSecretoglobinsTranscription Factor RelAasthmaepithelial barriermatrix metalloproteinase (MMP)plasticityzinc finger E-box binding homeobox 1 (ZEB1)

Identifiers

PMID38713619
PMCPMC11380976

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.