Evidence map›Paper›PMID 38713615›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2024

Effect of knocking out mouse

Subrata Sabui, Selvaraj Anthonymuthu, Kalidas Ramamoorthy, Jonathan Skupsky, Tara Sinta Kartika Jennings, Farah Rahmatpanah, James M Fleckenstein, Hamid M Said

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Regional organization of nutrient absorption across the small intestine.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  2. Review
  3. A new combined prognostic model involvingTranslational cancer research · 2025
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Subrata SabuiDepartment of Physiology and Biophysics, University of California, Irvine, California, United States.
Selvaraj AnthonymuthuDepartment of Physiology and Biophysics, University of California, Irvine, California, United States.ORCID 0000-0001-7316-1436
Kalidas RamamoorthyDepartment of Physiology and Biophysics, University of California, Irvine, California, United States.
Jonathan SkupskyVeterans Affairs Medical Center, Long Beach, California, United States.
Tara Sinta Kartika JenningsDepartment of Pathology and Laboratory Medicine, University of California, Irvine, California, United States.
Farah RahmatpanahDepartment of Pathology and Laboratory Medicine, University of California, Irvine, California, United States.
James M FleckensteinDivision of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States.
Hamid M SaidDepartment of Physiology and Biophysics, University of California, Irvine, California, United States.ORCID 0000-0003-1016-8547

Funding

Washington University DDRCC Supplemental Equipment RequestP30DK052574 · NIDDK · WASHINGTON UNIVERSITY · PI Jeffrey Wade Brown · 2000 to 2026
$30.8M
Novel Antigen Identification for an Enterotoxigenic E. coli VaccineR01AI089894 · NIAID · WASHINGTON UNIVERSITY · PI Zachary T. Berndsen, James Michael Fleckenstein · 2010 to 2026
$7.4M
Physiology/Pathophysiology of Vitamin B1 Transport in Pancreatic Acinar CellsR01AA018071 · NIAAA · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 2009 to 2023
$6.3M
Vitamin B1 (thiamin) transport in Alzheimer’s Disease: Role of microRNAs in regulating level of expression of its transporters (SLC19A2 & SLC19A3) in human brain cells and effect of hypoxiaR01DK056061 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 1999 to 2024
$5.0M
Mechanism/Regulation of Intestinal Thiamin UptakeR37DK056061 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 2009 to 2018
$3.6M
Molecular Pathogenesis of enterotoxigenic E. coli associated enteropathyR01AI170949 · NIAID · WASHINGTON UNIVERSITY · PI James Michael Fleckenstein · 2023 to 2026
$2.4M
Human Endogenous retroviruses as potential early markers for Alzheimer's diseaseR01CA226570 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI RAHMATPANAH, FARAH BAKHSHIAN · 2019 to 2023
$2.2M
DNA METHYLATION: PATTERNS AND POSSIBLE REGULATORY ROLESR01AG001807 · NIA · FLORIDA STATE UNIVERSITY · PI TAYLOR, J HERBERT · 1985 to 1985
–
Molecular Pathogenesis of Enterotoxigenic Escherichia coli InfectionsI01BX001469 · VA · ST. LOUIS VA MEDICAL CENTER · PI FLECKENSTEIN, JAMES MICHAEL · 2013 to 2017
–
BLRD Research Career Scientist Award ApplicationIK6BX006189 · VA · VETERANS HEALTH ADMINISTRATION · PI HAMID M SAID · 2023 to 2026
–
Physiological and Pathological Aspects of Intestinal Vitamin B2 AbsorptionI01BX001142 · VA · VETERANS HEALTH ADMINISTRATION · PI HAMID M SAID · 2011 to 2026
–
BLRD VA I01 BX001142BLRD VA I01 BX001469BLRD VA IK6 BX006189HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI089894HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) DK052574HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) DK56061HHS | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) AA018071HHS | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) AA-018071S1HHS | NIH | NIAID | Division of Microbiology and Infectious Diseases (DMID) AI170949NCI NIH HHS R01 CA226570NIAAA NIH HHS R01 AA018071NIAID NIH HHS R01 AI089894NIAID NIH HHS R01 AI170949NIDDK NIH HHS P30 DK052574NIDDK NIH HHS R01 DK056061NIDDK NIH HHS R37 DK056061U.S. Department of Veterans Affairs (VA) 5I01BX001469-05U.S. Department of Veterans Affairs (VA) I01BX001142U.S. Department of Veterans Affairs (VA) IK6BX006189
6 · The paper itself

Abstract

Humans and mammals obtain vitamin B1 from dietary and gut microbiota sources. A considerable amount of the microbiota-generated vitamin exists in the form of thiamine pyrophosphate (TPP), and colonocytes are capable of absorbing TPP via a specific carrier-mediated process that involves the colonic TPP transporter (cTPPT encoded by

Indexed as

ColonGastrointestinal MicrobiomeMice, KnockoutThiamine PyrophosphateAnimalsBiological TransportColitisHumansIntestinal AbsorptionMaleMembrane Transport ProteinsMiceMice, Inbred C57BLMembrane Transport ProteinsSLC44A4 protein, humanThiamine Pyrophosphatecolonic uptakegene knockoutgut microbiotaSlc44a4thiamine pyrophosphate

Identifiers

PMID38713615
PMCPMC11376973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.