Evidence map›Paper›PMID 38713263›Full record

ArticleJournal of gastroenterology2024

A novel artificial intelligence-based endoscopic ultrasonography diagnostic system for diagnosing the invasion depth of early gastric cancer.

Ryotaro Uema, Yoshito Hayashi, Takashi Kizu, Takumi Igura, Hideharu Ogiyama, Takuya Yamada, Risato Takeda, Kengo Nagai, Takuya Inoue, Masashi Yamamoto and 8 more

Abstract readValidation StudyMulticenter Study
In one paragraph

Article in Journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Ryotaro UemaDepartment of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yoshito HayashiDepartment of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Takashi KizuDepartment of Gastroenterology, Yao Municipal Hospital, Yao, 581-0069, Japan.
Takumi IguraDepartment of Gastroenterology, Sumitomo Hospital, Osaka, 530-0005, Japan.
Hideharu OgiyamaDepartment of Gastroenterology, Ikeda Municipal Hospital, Ikeda, 563-0025, Japan.
Takuya YamadaDepartment of Gastroenterology, Osaka Rosai Hospital, Sakai, 591-8025, Japan.
Risato TakedaDepartment of Gastroenterology, Itami City Hospital, Itami, 664-0015, Japan.
Kengo NagaiDepartment of Gastroenterology, Suita Municipal Hospital, Suita, 564-0018, Japan.
Takuya InoueDepartment of Gastroenterology, Osaka General Medical Center, Osaka, 558-8558, Japan.
Masashi YamamotoDepartment of Gastroenterology, Toyonaka Municipal Hospital, Toyonaka, 560-8565, Japan.
Shinjiro YamaguchiDepartment of Gastroenterology, Kansai Rosai Hospital, Amagasaki, 660-0064, Japan.
Takashi KanesakaDepartment of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, 540-0008, Japan.
Takeo YoshiharaDepartment of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Minoru KatoDepartment of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Shunsuke YoshiiDepartment of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yoshiki TsujiiDepartment of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Shinichiro ShinzakiDepartment of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Tetsuo TakeharaDepartment of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan. takehara@gh.med.osaka-u.ac.jp.ORCID http://orcid.org/0000-0001-5036-3457

Funding

JSPS KAKENHI JP22K18210
6 · The paper itself

Abstract

backgroundWe developed an artificial intelligence (AI)-based endoscopic ultrasonography (EUS) system for diagnosing the invasion depth of early gastric cancer (EGC), and we evaluated the performance of this system.

methodsA total of 8280 EUS images from 559 EGC cases were collected from 11 institutions. Within this dataset, 3451 images (285 cases) from one institution were used as a development dataset. The AI model consisted of segmentation and classification steps, followed by the CycleGAN method to bridge differences in EUS images captured by different equipment. AI model performance was evaluated using an internal validation dataset collected from the same institution as the development dataset (1726 images, 135 cases). External validation was conducted using images collected from the other 10 institutions (3103 images, 139 cases).

resultsThe area under the curve (AUC) of the AI model in the internal validation dataset was 0.870 (95% CI: 0.796-0.944). Regarding diagnostic performance, the accuracy/sensitivity/specificity values of the AI model, experts (n = 6), and nonexperts (n = 8) were 82.2/63.4/90.4%, 81.9/66.3/88.7%, and 68.3/60.9/71.5%, respectively. The AUC of the AI model in the external validation dataset was 0.815 (95% CI: 0.743-0.886). The accuracy/sensitivity/specificity values of the AI model (74.1/73.1/75.0%) and the real-time diagnoses of experts (75.5/79.1/72.2%) in the external validation dataset were comparable.

conclusionsOur AI model demonstrated a diagnostic performance equivalent to that of experts.

Indexed as

Artificial IntelligenceEndosonographyNeoplasm InvasivenessStomach NeoplasmsAdultAgedAged, 80 and overArea Under CurveEarly Detection of CancerFemaleHumansMaleMiddle AgedSensitivity and SpecificityArtificial intelligenceDeep learningEarly gastric cancerEndoscopic ultrasonography

Identifiers

PMID38713263
PMCPMC11217111

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.