Evidence map›Paper›PMID 38713233›Full record

ArticleApplied microbiology and biotechnology2024

An unexpected role of EasD

Zhi-Pu Yu, Chunyan An, Yongpeng Yao, Ju-Zhang Yan, Shu-Shan Gao, Yu-Cheng Gu, Chang-Yun Wang, Chengsen Cui

Abstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. EngineeringFrontiers in microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhi-Pu YuKey Laboratory of Marine Drugs, The Ministry of Education of China, Institute of Evolution & Marine Biodiversity, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, People's Republic of China.
Chunyan AnTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.
Yongpeng YaoState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
Ju-Zhang YanLaboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266003, People's Republic of China.
Shu-Shan GaoLaboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266003, People's Republic of China.
Yu-Cheng GuLaboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266003, People's Republic of China. yucheng.gu@syngenta.com.
Chang-Yun WangKey Laboratory of Marine Drugs, The Ministry of Education of China, Institute of Evolution & Marine Biodiversity, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, People's Republic of China. changyun@ouc.edu.cn.
Chengsen CuiLaboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266003, People's Republic of China. cuichs@tib.cas.cn.ORCID http://orcid.org/0000-0002-6867-1826

Funding

National Key Research and Development Program of China 2019YFA0905100 and 2018YFA0901600the Major Project of Qingdao Marine Science and Technology Center 2022QNLM030003-1Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project TSBICIP-CXRC-062Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project TSBICIP-CXRC-069
6 · The paper itself

Abstract

Ergot alkaloids (EAs) are a diverse group of indole alkaloids known for their complex structures, significant pharmacological effects, and toxicity to plants. The biosynthesis of these compounds begins with chanoclavine-I aldehyde (CC aldehyde, 2), an important intermediate produced by the enzyme EasD

Indexed as

AldehydesErgot AlkaloidsCatalytic DomainMolecular Docking SimulationMutagenesis, Site-DirectedOxidation-ReductionOxidoreductasesAldehydesErgot AlkaloidsOxidoreductasesCC acidEasDafErgot alkaloidOxidations

Identifiers

PMID38713233
PMCPMC11076337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.