Evidence map›Paper›PMID 38712396›Full record

Observational studyGut and liver2024

Risk of Ischemic Stroke in Relation to

Eun-Bi Jeon, Nayoung Kim, Beom Joon Kim, In-Chang Hwang, Sang Bin Kim, Ji-Hyun Kim, Yonghoon Choi, Yu Kyung Jun, Hyuk Yoon, Cheol Min Shin and 3 more

Abstract readObservational Study
In one paragraph

Observational study in Gut and liver, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effect ofFrontiers in medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Eun-Bi JeonDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0003-0021-8600
Nayoung KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-9397-0406
Beom Joon KimDepartment of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-2719-3012
In-Chang HwangDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0003-4966-3924
Sang Bin KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-6884-9516
Ji-Hyun KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0009-0007-5482-9120
Yonghoon ChoiDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-1331-969X
Yu Kyung JunDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-4046-8578
Hyuk YoonDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-2657-0349
Cheol Min ShinDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0003-2265-9845
Young Soo ParkDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0003-1893-7726
Dong Ho LeeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-6376-410X
Soyeon AhnMedical Research Collaborating Center, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0003-3440-2027

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims: : A few studies have suggested the association between Methods: : This prospective observational cohort study was conducted at Seoul National University Bundang Hospital, from May 2003 to February 2023, and involved gastroscopy-based HP testing. Propensity score (PS) matching was employed to ensure balanced groups by matching patients in the HP eradicated group (n=2,803) in a 3:1 ratio with patients in the HP non-eradicated group (n=960). Cox proportional hazard regression analysis was used to evaluate the risk of ischemic stroke. Results: : Among 6,664 patients, multivariate analysis after PS matching indicated that HP eradication did not significantly alter the risk of ischemic stroke (hazard ratio, 0.531; 95% confidence interval, 0.221 to 1.270; p=0.157). Sex-specific subgroup analyses, both univariate and multivariate, did not yield statistically significant differences. However, Kaplan-Meier analysis revealed a potential trend: the females in the HP eradicated group exhibited a lower incidence of ischemic stroke than those in the HP non-eradicated group, although this did not reach statistical significance (p=0.057). Conclusions: : This finding suggests that HP eradication might not impact the risk of ischemic stroke. However, there was a trend showing that females potentially had a lower risk of ischemic stroke following HP eradication, though further investigation is required to establish definitive evidence.

Indexed as

Helicobacter InfectionsHelicobacter pyloriIschemic StrokeAdultAgedFemaleHumansIncidenceKaplan-Meier EstimateMaleMiddle AgedPropensity ScoreProportional Hazards ModelsProspective StudiesRepublic of KoreaRisk FactorsEradicationIschemic strokeSex

Identifiers

PMID38712396
PMCPMC11249949

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.