ArticlebioRxiv : the preprint server for biology2025
Abstract readPreprint
In one paragraph
Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Herpes simplex virus 1 accelerates the progression of Alzheimer's disease by modulating microglial phagocytosis and activating NLRP3 pathway.Journal of neuroinflammation · 2024Article
Corrections and comments
- Updated by
Authors and funding
25 authors.
Sarah NaguibHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Chloe Lopez-LeeHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Eileen Ruth TorresHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Se-In LeeHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Jingjie ZhuHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Daphne ZhuHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Pearly YeHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Kendra NormanHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Mingrui ZhaoHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Man Ying WongHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Yohannes A AmbawCell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY.
Rodrigo CastanedaHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Wei WangHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Tark PatelDepartment of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Maitreyee BhagwatHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Rada NorinskyTransgenic and Reproductive Technology Center, Rockefeller University, New York, NY.
Sue-Ann MokDepartment of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Tobias C WaltherHoward Hughes Medical Institute, New York, NY, USA.
Robert V FareseCell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY.
Wenjie LuoHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Subhash SinhaHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.ORCID 0000-0001-8916-5677
Zhuhao WuHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Li FanHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Shiaoching GongHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Li GanHelen and Robert Appel Institute for Alzheimer's Disease Research, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Funding
Elucidate the roles of Alzheimer's disease risk genes and variants in gene expression and AD-related phenotypesRF1AG079557 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GAN, LI, SHEN, YIN · 2022 to 2025
$6.1MStudy of Selective Cell and System Vulnerability in Alzheimer's DiseaseR01AG079291 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Li Gan, Yun Li · 2023 to 2026
$5.4McGAS inhibitors for Alzheimer's disease treatmentR01AG074541 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI GAN, LI, SINHA, SUBHASH C · 2021 to 2025
$4.2MMaladaptive antiviral pathways in Alzheimer's diseaseR01AG072758 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI GAN, LI · 2021 to 2025
$4.1MElucidating the Cell-Type Specific Neuroprotective Mechanisms in the APOE3 Christchurch Mutation in Alzheimer's DiseaseF32AG085960 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Sarah A Naguib · 2024 to 2026
$197kNIA NIH HHS F32 AG085960NIA NIH HHS R01 AG072758NIA NIH HHS R01 AG074541NIA NIH HHS R01 AG079291NIA NIH HHS RF1 AG079557
Abstract
The Christchurch mutation (R136S) on the
Indexed as
Alzheimer’sAPOEcGASChristchurchinterferonmicrogliatauopathy
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.