Evidence map›Paper›PMID 38712136›Full record

ArticlebioRxiv : the preprint server for biology2024

A latent variable model for evaluating mutual exclusivity and co-occurrence between driver mutations in cancer.

Ahmed Shuaibi, Uthsav Chitra, Benjamin J Raphael

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ahmed ShuaibiDepartment of Computer Science, Princeton University.
Uthsav ChitraDepartment of Computer Science, Princeton University.
Benjamin J RaphaelDepartment of Computer Science, Princeton University.ORCID 0000-0003-1274-048X

Funding

Comprehensive and Robust Tools for Analysis of Tumor Heterogeneity and EvolutionU24CA248453 · NCI · PRINCETON UNIVERSITY · PI Benjamin Raphael · 2020 to 2026
$4.7M
Pathway, Network and Spatiotemporal Integration of Cancer Genomics DataU24CA264027 · NCI · PRINCETON UNIVERSITY · PI RAPHAEL, BENJAMIN, YEH, JEN JEN · 2021 to 2025
$1.5M
NCI NIH HHS U24 CA248453NCI NIH HHS U24 CA264027
6 · The paper itself

Abstract

A key challenge in cancer genomics is understanding the functional relationships and dependencies between combinations of somatic mutations that drive cancer development. Such

Identifiers

PMID38712136
PMCPMC11071465

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.