Evidence map›Paper›PMID 38712066›Full record

ArticlebioRxiv : the preprint server for biology2025

Predicting gene expression responses to environment in

Margarita Takou, Emily S Bellis, Jesse R Lasky

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Margarita TakouPennsylvania State University, University Park, 16802, USA.
Emily S BellisPennsylvania State University, University Park, 16802, USA.ORCID 0000-0001-6066-1466
Jesse R LaskyPennsylvania State University, University Park, 16802, USA.

Funding

Evolutionary genetics of genotype-by-environment interactions for complex traitsR35GM138300 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI LASKY, JESSE · 2020 to 2024
$1.8M
NIGMS NIH HHS R35 GM138300
6 · The paper itself

Abstract

The evolution of gene expression responses is a critical component of adaptation to variable environments. Predicting how DNA sequence influences expression is challenging because the genotype to phenotype map is not well resolved for

Indexed as

evolutiongene expression predictiongenotype to phenotype maplow frequency variantsmachine learningregulatory elements

Identifiers

PMID38712066
PMCPMC11071634

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.