Evidence map›Paper›PMID 38712061›Full record

ArticlebioRxiv : the preprint server for biology2024

Regulation of Microprocessor assembly and localization via Pasha's WW domain in

Brooke E Montgomery, Thiago L Knittel, Kailee J Reed, Madeleine C Chong, Ida J Isolehto, Erin R Cafferty, Margaret J Smith, Reese A Sprister, Colin N Magelky, Hataichanok Scherman and 2 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Brooke E MontgomeryDepartment of Biology, Colorado State University, Fort Collins, CO 80523, USA.
Thiago L KnittelDepartment of Biology, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0001-5716-2033
Kailee J ReedDepartment of Biology, Colorado State University, Fort Collins, CO 80523, USA.
Madeleine C ChongDepartment of Biology, Colorado State University, Fort Collins, CO 80523, USA.
Ida J IsolehtoBiology of Non-coding RNA group, Institute of Molecular Biology, Mainz, Germany.
Erin R CaffertyDepartment of Biology, Colorado State University, Fort Collins, CO 80523, USA.
Margaret J SmithDepartment of Biology, Colorado State University, Fort Collins, CO 80523, USA.
Reese A SpristerDepartment of Biology, Colorado State University, Fort Collins, CO 80523, USA.
Colin N MagelkyDepartment of Biology, Colorado State University, Fort Collins, CO 80523, USA.
Hataichanok SchermanDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA.
Rene F KettingBiology of Non-coding RNA group, Institute of Molecular Biology, Mainz, Germany.
Taiowa A MontgomeryDepartment of Biology, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0001-7857-3253

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Mechanism and function of small RNAs in development and gene silencing in the germlineR35GM119775 · NIGMS · COLORADO STATE UNIVERSITY · PI Taiowa Akoni Montgomery · 2016 to 2026
$4.3M
NIGMS NIH HHS R35 GM119775NIH HHS P40 OD010440
6 · The paper itself

Abstract

Primary microRNA (pri-miRNA) transcripts are processed by the Microprocessor, a protein complex that includes the ribonuclease Drosha and its RNA binding partner DGCR8/Pasha. We developed a live, whole animal, fluorescence-based sensor that reliably monitors pri-miRNA processing with high sensitivity in

Identifiers

PMID38712061
PMCPMC11071396

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.