Evidence map›Paper›PMID 38712050›Full record

ArticlebioRxiv : the preprint server for biology2025

The

Brianna Steiert, Cherilyn A Elwell, Xavier Tijerina, Madison A Elliott, Yennifer Delgado, Jocelyn Ni, Robert Faris, Parker Smith, Shelby E Andersen, Paige N McCaslin and 15 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Brianna SteiertDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Cherilyn A ElwellDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Xavier TijerinaDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Madison A ElliottDepartment of Developmental and Cell Biology, University of California, Irvine, California, USA.
Yennifer DelgadoDepartment of Microbiology, Immunology, and Molecular Genetics (MIMG), University of California, Los Angeles, Los Angeles, CA, USA.
Jocelyn NiDepartment of Microbiology, Immunology, and Molecular Genetics (MIMG), University of California, Los Angeles, Los Angeles, CA, USA.
Robert FarisDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Parker SmithDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Shelby E AndersenDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Paige N McCaslinDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Julia Kevil-YeagerDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Quinn EldridgeDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Brian S ImaiProtein Sciences Facility, Roy J. Carver Biotechnology Center, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Justine V ArringtonProtein Sciences Facility, Roy J. Carver Biotechnology Center, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Peter M YauProtein Sciences Facility, Roy J. Carver Biotechnology Center, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Kathleen M MirrashidiDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Jeffrey R JohnsonQB3, California Institute for Quantitative Biosciences, San Francisco, CA 94148, USA.
Erik VerschuerenQB3, California Institute for Quantitative Biosciences, San Francisco, CA 94148, USA.
John Von DollenQB3, California Institute for Quantitative Biosciences, San Francisco, CA 94148, USA.
Gwendolyn M JangQB3, California Institute for Quantitative Biosciences, San Francisco, CA 94148, USA.
Nevan J KroganQB3, California Institute for Quantitative Biosciences, San Francisco, CA 94148, USA.ORCID 0000-0003-4902-337X
Mehdi BouhaddouDepartment of Microbiology, Immunology, and Molecular Genetics (MIMG), University of California, Los Angeles, Los Angeles, CA, USA.
Christine SuetterlinDepartment of Developmental and Cell Biology, University of California, Irvine, California, USA.
Joanne N EngelDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.ORCID 0000-0002-2168-9711
Mary M WeberDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.

Funding

X-ray Screening and Rapid Structure DeterminationP50GM082250 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KROGAN, NEVAN J · 2007 to 2018
$48.8M
The Burden of Chikungunya and Dengue Infection in KenyaU54AI081680 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI RYMAN, KATHERINE D · 2009 to 2013
$40.4M
Virus CoreU19AI106754 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SHAW, MEGAN LOUISE · 2013 to 2017
$26.0M
Molecular Virology and Systems Biology Screening CoreP01AI090935 · NIAID · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI YOUNG, JOHN A T · 2010 to 2014
$20.4M
Rewiring Therapeutic Cells: User-Controlled T Cells and Stem CellsP50GM081879 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LIM, WENDELL A · 2010 to 2017
$19.0M
TRAINING IN MECHANISMS OF PARASITISMT32AI007511 · NIAID · UNIVERSITY OF IOWA · PI BUTLER, NOAH SULLIVAN, WEBER, MARY · 1996 to 2025
$8.1M
Microbial Pathogenesis and Host DefenseT32AI060537 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joanne N. Engel · 2004 to 2026
$6.5M
Novel approaches to identify host genes required for Chlamydia pathogenesisR01AI073770 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ENGEL, JOANNE N. · 2007 to 2016
$3.8M
Functional characterization of Chlamydia trachomatis inclusion membrane proteins and their role in subversion of the host vesicular traffickingR01AI150812 · NIAID · UNIVERSITY OF IOWA · PI Mary Weber · 2020 to 2026
$3.5M
The role of secreted effector proteins in Chlamydia trachomatis invasionR01AI155434 · NIAID · UNIVERSITY OF IOWA · PI WEBER, MARY · 2020 to 2024
$2.5M
MARC at University of IowaT34GM141143 · NIGMS · UNIVERSITY OF IOWA · PI ADAMS-PHILLIPS, LORI C, FORBES, TORI · 2021 to 2024
$1.5M
Development of genetic tools for overexpression and targeted mutagenesis of Orientia tsutsugamushi TPR proteinsR61AI179999 · NIAID · UNIVERSITY OF IOWA · PI Mary Weber · 2024 to 2026
$680k
NIAID NIH HHS P01 AI090935NIAID NIH HHS R01 AI073770NIAID NIH HHS R01 AI150812NIAID NIH HHS R01 AI155434NIAID NIH HHS R21 AI105561NIAID NIH HHS R61 AI179999NIAID NIH HHS T32 AI007511NIAID NIH HHS T32 AI060537NIAID NIH HHS U19 AI106754NIAID NIH HHS U54 AI081680NIGMS NIH HHS P50 GM081879NIGMS NIH HHS P50 GM082250NIGMS NIH HHS T34 GM141143
6 · The paper itself

Abstract

To usurp host defenses and establish a replicative niche, obligate intracellular pathogens are tasked with remodeling the host cell using a comparatively small repertoire of effector proteins. For

Indexed as

CebNChlamydia trachomatisCT584IncnucleoporinRae1T3SS effector

Identifiers

PMID38712050
PMCPMC11071493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.