Evidence map›Paper›PMID 38711974›Full record

ArticleFrontiers in microbiology2024

Zinc oxide nanoparticles mediate bacterial toxicity in Mueller-Hinton Broth via Zn

Alexander J Caron, Iman J Ali, Michael J Delgado, Dustin Johnson, John M Reeks, Yuri M Strzhemechny, Shauna M McGillivray

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
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  12. The effect of biosynthesized zinc oxide nanoparticles on gene expression and apoptosis in triple-negative breast cancer cells.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexander J CaronDepartment of Biology, Texas Christian University, Fort Worth, TX, United States.
Iman J AliDepartment of Biology, Texas Christian University, Fort Worth, TX, United States.
Michael J DelgadoDepartment of Biology, Texas Christian University, Fort Worth, TX, United States.
Dustin JohnsonDepartment of Physics and Astronomy, Texas Christian University, Fort Worth, TX, United States.
John M ReeksDepartment of Physics and Astronomy, Texas Christian University, Fort Worth, TX, United States.
Yuri M StrzhemechnyDepartment of Physics and Astronomy, Texas Christian University, Fort Worth, TX, United States.
Shauna M McGillivrayDepartment of Biology, Texas Christian University, Fort Worth, TX, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As antibiotic resistance increases and antibiotic development dwindles, new antimicrobial agents are needed. Recent advances in nanoscale engineering have increased interest in metal oxide nanoparticles, particularly zinc oxide nanoparticles, as antimicrobial agents. Zinc oxide nanoparticles are promising due to their broad-spectrum antibacterial activity and low production cost. Despite many studies demonstrating the effectiveness of zinc oxide nanoparticles, the antibacterial mechanism is still unknown. Previous work has implicated the role of reactive oxygen species such as hydrogen peroxide, physical damage of the cell envelope, and/or release of toxic Zn

Indexed as

metal oxidesnanoantibioticsnanoparticlesStaphylococcus aureuszinc oxidezinc toxicity

Identifiers

PMID38711974
PMCPMC11070567

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.