ReviewFrontiers in toxicology2024
Abusive use of anabolic androgenic steroids, male sexual dysfunction and infertility: an updated review.
Review in Frontiers in toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Cardiovascular Implications of the Enhanced Games: Performance Enhancing Drugs in Competition and Recreation.Sports medicine - open · 2026Review
- Comprehensive metabolic profiling of fluoxymesterone in vivo by GC-Orbitrap HRMS: a integrated strategy for novel biomarkers discovery in doping analysis.Analytical and bioanalytical chemistry · 2026Article
- The effects of different doses of Stanozolol on sperm parameters and testicular histology in male rats: An experimental study.International journal of reproductive biomedicine · 2026Article
- Exercise ameliorates stanozolol and cannabis co-abuse testicular damage in rats evidenced by biochemical and histological regulation of SIRT1 and STS.Scientific reports · 2025Article
- Impact of lifestyle and environmental factors on fertility.Current opinion in urology · 2025Review
- Changing trends in anabolic-androgenic steroid use within Scottish prisons: Detection, prevalence, and quantitation.Drug testing and analysis · 2025Article
- Unveiling the global landscape of anabolic steroid residues in beef via integrated targeted quantification and high-resolution suspect screening.Current research in food science · 2025Article
- Pandemic of testosterone abuse: Considerations for male fertility.Arab journal of urology · 2025Review
- Immediate and late effects of supraphysiological doses of nandrolone decanoate on the testis of rats.Acta cirurgica brasileira · 2025Article
- The WHO 2025 Guideline for the Prevention, Diagnosis and Treatment of Infertility: A Comprehensive Review with Focus on Male Reproductive Health.International braz j urol : official journal of the Brazilian Society of UrologyReview
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evolving prevalence of anabolic androgenic steroids (AAS) abuse among nonathletes is alarming because of the known harm to an individual's health. Among the adverse effects of AAS abuse, male infertility and sexual dysfunction have been often reported in the literature, but little is known regarding its actual prevalence, possible underpinning mechanisms, and potential treatments either during or post-AAS usage. Thus, the current narrative review summarizes the state-of-art regarding the effects of AAS on male fertility and sexual function. Evidence was gathered from the latest reviews and recent original studies, specifically from prospective cohorts and clinical trials, ultimately resulting in five main topics of discussion. First, AAS usage is briefly characterized by its historical background, main physiological mechanisms, and the most frequently used AAS substances. Second, data on the prevalence of AAS-induced male infertility and sexual dysfunction are described. Third, some new insights on possible underpinning mechanisms of AAS-induced male infertility and sexual dysfunction are thoroughly discussed, with particular attention to histological data derived from animal models and the latest insights from prospective cohorts in humans. Fourth, the potential treatments during and after the AAS usage are presented, highlighting the odds of resolving male infertility and sexual dysfunction. Fifth, future directions on this topic are discussed, focusing on the methodological robustness of scientific studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.