Evidence map›Paper›PMID 38711586›Full record

ArticleBeilstein journal of organic chemistry2024

One-pot Ugi-azide and Heck reactions for the synthesis of heterocyclic systems containing tetrazole and 1,2,3,4-tetrahydroisoquinoline.

Jiawei Niu, Yuhui Wang, Shenghu Yan, Yue Zhang, Xiaoming Ma, Qiang Zhang, Wei Zhang

Abstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiawei Niu *School of Pharmacy, Changzhou University, 1 Gehu Road, Changzhou 213164, China.
Yuhui Wang *School of Pharmacy, Changzhou University, 1 Gehu Road, Changzhou 213164, China.
Shenghu YanSchool of Pharmacy, Changzhou University, 1 Gehu Road, Changzhou 213164, China.
Yue ZhangSchool of Pharmacy, Changzhou University, 1 Gehu Road, Changzhou 213164, China.
Xiaoming MaSchool of Pharmacy, Changzhou University, 1 Gehu Road, Changzhou 213164, China.ORCID https://orcid.org/0000-0003-1358-428X
Qiang ZhangSchool of Chemistry and Life Sciences, Suzhou University of Science and Technology, 99 Xuefu Road, Suzhou 215009, China.ORCID https://orcid.org/0000-0002-8173-8722
Wei ZhangDepartment of Chemistry and Center for Green Chemistry, University of Massachusetts Boston, 100 Morrissey Blvd, Boston, MA 02125, USA.ORCID https://orcid.org/0000-0002-6097-2763

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new method for the synthesis of heterocyclic systems containing tetrazole and tetrahydroisoquinoline is developed via the performance of one-pot Ugi-azide and Heck cyclization reactions. The integration of the multicomponent and post-condensation reactions in one-pot maximizes the pot-, atom-, and step-economy (PASE).

Indexed as

Heck reactionone-pottetrahydroisoquinolinetetrazoletetrazolo-pyrazino[2,1-a]isoquinolin-6(5H)-onesUgi-azide reaction

Identifiers

PMID38711586
PMCPMC11070971

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.