Evidence map›Paper›PMID 38711366›Full record

ArticleAnalytical chemistry2024

Structural Elucidation of Ubiquitin via Gas-Phase Ion/Ion Cross-Linking Reactions Using Sodium-Cationized Reagents Coupled with Infrared Multiphoton Dissociation.

Woo-Young Kang, Arup Mondal, Julia R Bonney, Alberto Perez, Boone M Prentice

Abstract read
In one paragraph

Article in Analytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Analytical applications of gas-phase ion chemistry enabled by mass spectrometry.Analytical methods : advancing methods and applications · 2026
    Review
  2. Article
  3. Article
  4. MELD in Action: Harnessing Data to Accelerate Molecular Dynamics.Journal of chemical information and modeling · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Woo-Young KangDepartment of Chemistry, University of Florida, Gainesville, Florida 32611, United States.
Arup MondalDepartment of Chemistry, University of Florida, Gainesville, Florida 32611, United States.ORCID 0000-0002-8970-3380
Julia R BonneyDepartment of Chemistry, University of Florida, Gainesville, Florida 32611, United States.
Alberto PerezDepartment of Chemistry, University of Florida, Gainesville, Florida 32611, United States.
Boone M PrenticeDepartment of Chemistry, University of Florida, Gainesville, Florida 32611, United States.ORCID 0000-0002-1927-9457

Funding

Imaging mass spectrometry at isomeric chemical resolution using gas phase ion/ion reactionsR01GM138660 · NIGMS · UNIVERSITY OF FLORIDA · PI PRENTICE, BOONE M. · 2020 to 2024
$1.6M
Targeting the ET domain of BET proteins: specificity and selectivityR01GM149646 · NIGMS · UNIVERSITY OF FLORIDA · PI Alberto Perez · 2023 to 2026
$1.2M
NIGMS NIH HHS R01 GM138660NIGMS NIH HHS R01 GM149646
6 · The paper itself

Abstract

Accurate structural determination of proteins is critical to understanding their biological functions and the impact of structural disruption on disease progression. Gas-phase cross-linking mass spectrometry (XL-MS) via ion/ion reactions between multiply charged protein cations and singly charged cross-linker anions has previously been developed to obtain low-resolution structural information on proteins. This method significantly shortens experimental time relative to conventional solution-phase XL-MS but has several technical limitations: (1) the singly deprotonated

Indexed as

Cross-Linking ReagentsMass SpectrometryUbiquitinCationsGasesIonsSodiumSuccinimidesCationsCross-Linking ReagentsGasesIonsSodiumSuccinimidesUbiquitin

Identifiers

PMID38711366
PMCPMC11161031

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.