Evidence map›Paper›PMID 38711364›Full record

ArticleCancer medicine2024

Association of patient socioeconomic status with outcomes after palliative treatment for disseminated cancer.

Richard C Maduka, Maureen E Canavan, Samantha L Walters, Theresa Ermer, Peter L Zhan, Michael F Kaminski, Andrew X Li, Matthew D Pichert, Michelle C Salazar, Elizabeth H Prsic and 1 more

Abstract read
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Richard C MadukaDivision of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0003-1338-0199
Maureen E CanavanDivision of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-9410-3542
Samantha L WaltersDivision of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.
Theresa ErmerDivision of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.
Peter L ZhanDivision of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.
Michael F KaminskiDivision of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.
Andrew X LiDivision of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.
Matthew D PichertDivision of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.
Michelle C SalazarDivision of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.
Elizabeth H PrsicPalliative Care Program, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Daniel J BoffaDivision of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-5471-8833

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Cancer Center Advanced Training Program for Physician-Scientists (YCC-ATPP)T32CA233414 · NCI · YALE UNIVERSITY · PI Eric P. Winer · 2019 to 2026
$3.2M
Short Term Research Training: Students in Health Professional SchoolsT35DK104689 · NIDDK · YALE UNIVERSITY · PI LLOYD G CANTLEY, Sarwat I Chaudhry · 2015 to 2026
$2.6M
NCATS NIH HHS UL1 TR001863NCI NIH HHS T32 CA233414NIDDK NIH HHS T35 DK104689NIEHS NIH HHS T32 CA233414
6 · The paper itself

Abstract

backgroundPalliative treatment has been associated with improved quality of life and survival for a wide variety of metastatic cancers. However, it is unclear whether the benefits of palliative treatment are uniformly experienced across the US cancer population. We evaluated patterns and outcomes of palliative treatment based on socioeconomic, sociodemographic and treating facility characteristics.

methodsPatients diagnosed between 2008 and 2019 with Stage IV primary cancer of nine organ sites were analyzed in the National Cancer Database. The association between identified variables, and outcomes concerning the administration of palliative treatment were analyzed with multivariable logistic regression and Cox proportional hazard models.

resultsOverall 238,995 (23.6%) of Stage IV patients received palliative treatment, which increased over time for all cancers (from 20.7% in 2008 to 25.6% in 2019). Palliative treatment utilization differed significantly by region (West less than Northeast, OR: 0.55 [0.54-0.56], p < 0.001) and insurance payer status (uninsured greater than private insurance, OR: 1.35 [1.32-1.39], p < 0.001). Black race and Hispanic ethnicity were also associated with lower rates of palliative treatment compared to White and non-Hispanics respectively (OR for Blacks: 0.91 [0.90-0.93], p < 0.001 and OR for Hispanics: 0.79 [0.77-0.81] p < 0.001).

conclusionsThere are important differences in the utilization of palliative treatment across different populations in the United States. A better understanding of variability in palliative treatment use and outcomes may identify opportunities to improve informed decision making and optimize quality of care at the end-of-life.

Indexed as

NeoplasmsPalliative CareSocial ClassAdultAgedFemaleHumansMaleMiddle AgedNeoplasm StagingQuality of LifeTreatment OutcomeUnited Statescancer educationcancer managementchemotherapypalliative treatment

Identifiers

PMID38711364
PMCPMC11074703

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.