Evidence map›Paper›PMID 38711351›Full record

GuidelineCanadian journal of psychiatry. Revue canadienne de psychiatrie2024

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2023 Update on Clinical Guidelines for Management of Major Depressive Disorder in Adults: Réseau canadien pour les traitements de l'humeur et de l'anxiété (CANMAT) 2023 : Mise à jour des lignes directrices cliniques pour la prise en charge du trouble dépressif majeur chez les adultes.

Raymond W Lam, Sidney H Kennedy, Camelia Adams, Anees Bahji, Serge Beaulieu, Venkat Bhat, Pierre Blier, Daniel M Blumberger, Elisa Brietzke, Trisha Chakrabarty and 34 more

Erratum issued Registry-linked trialAbstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07574658 (Brief Cognitive Behavioral Therapy for Suicide Prevention in a Brazilian Sample), which is not on this map. Cited by 187 papers, 20 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed, 20 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07574658 phase3not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Brief Cognitive Behavioral Therapy for Suicide Prevention in a Brazilian Sample: a Study Protocol of a Randomized Clinical Trial

TypeinterventionalSponsorUniversity of Sao PauloRan2026 to 2028Enrolled150ConditionsSuicide Ideation, Suicide AttemptsArmsBrief Cognitive-Behavioral Therapy (BCBT) for Suicide Prevention, Supportive Therapy
3 · Its place in the literature

Who cites it

187 citing papers in PubMed, 20 syntheses or guidelines pooled it.

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127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

44 authors.

Raymond W LamDepartment of Psychiatry, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0001-7142-4669
Sidney H KennedyDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0001-5339-7185
Camelia AdamsDepartment of Psychiatry, University of Saskatchewan, Saskatoon, SK, Canada.ORCID 0000-0001-5253-1426
Anees BahjiDepartment of Psychiatry, University of Calgary, Calgary, AB, Canada.
Serge BeaulieuDepartment of Psychiatry, McGill University, Montréal, QC, Canada.ORCID 0000-0001-6921-3870
Venkat BhatDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.
Pierre BlierDepartment of Psychiatry, University of Ottawa, Ottawa, ON, Canada.
Daniel M BlumbergerDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-8422-5818
Elisa BrietzkeDepartment of Psychiatry, Queen's University, Kingston, ON, Canada.
Trisha ChakrabartyDepartment of Psychiatry, University of British Columbia, Vancouver, BC, Canada.
André DoDepartment of Psychiatry, Université de Montréal, Montréal, QC, Canada.
Benicio N FreyDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Peter GiacobbeDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0001-6642-6221
David GratzerDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-4578-0050
Sophie GrigoriadisDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-3461-6850
Jeffrey HabertDepartment of Family and Community Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-0009-3182
M Ishrat HusainDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0001-5771-5750
Zahinoor IsmailDepartment of Psychiatry, University of Calgary, Calgary, AB, Canada.ORCID 0000-0002-5529-3731
Alexander McGirrDepartment of Psychiatry, University of Calgary, Calgary, AB, Canada.ORCID 0000-0002-8425-3958
Roger S McIntyreDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.
Erin E MichalakDepartment of Psychiatry, University of British Columbia, Vancouver, BC, Canada.
Daniel J MüllerDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-4978-4400
Sagar V ParikhDepartment of Psychiatry, University of Michigan, Ann Arbour, MI, USA.
Lena C QuiltyDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-0934-4363
Arun V RavindranDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-1655-2753
Nisha RavindranDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-0468-1099
Johanne RenaudDepartment of Psychiatry, McGill University, Montréal, QC, Canada.ORCID 0000-0002-8060-2890
Joshua D RosenblatDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-4773-2191
Zainab SamaanDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Gayatri SarafDepartment of Psychiatry, University of Ottawa, Ottawa, ON, Canada.
Kathryn SchadeOffice of Research Services, Huron University, London, ON, Canada.
Ayal SchafferDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.
Mark SinyorDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-7756-2584
Claudio N SoaresDepartment of Psychiatry, Queen's University, Kingston, ON, Canada.
Jennifer SwainsonDepartment of Psychiatry, University of Alberta, Edmonton, AB, Canada.
Valerie H TaylorDepartment of Psychiatry, University of Calgary, Calgary, AB, Canada.ORCID 0000-0002-8948-638X
Smadar V TourjmanDepartment of Psychiatry, Université de Montréal, Montréal, QC, Canada.ORCID 0000-0002-2264-9586
Rudolf UherDepartment of Psychiatry, Dalhousie University, Halifax, NS, Canada.ORCID 0000-0002-2998-0546
Michael van AmeringenDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Gustavo VazquezDepartment of Psychiatry, Queen's University, Kingston, ON, Canada.ORCID 0000-0002-2918-3336
Simone VigodDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.
Daphne VoineskosDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-7450-4434
Lakshmi N YathamDepartment of Psychiatry, University of British Columbia, Vancouver, BC, Canada.
Roumen V MilevDepartment of Psychiatry, Queen's University, Kingston, ON, Canada.ORCID 0000-0001-6884-171X

Funding

Mentoring the next generation of addiction clinician scientists while responding to the opioid epidemicR25DA037756 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI FAIRBAIRN, NADIA · 2014 to 2023
$3.6M
NIDA NIH HHS R25 DA037756
6 · The paper itself

Abstract

backgroundThe Canadian Network for Mood and Anxiety Treatments (CANMAT) last published clinical guidelines for the management of major depressive disorder (MDD) in 2016. Owing to advances in the field, an update was needed to incorporate new evidence and provide new and revised recommendations for the assessment and management of MDD in adults.

methodsCANMAT convened a guidelines editorial group comprised of academic clinicians and patient partners. A systematic literature review was conducted, focusing on systematic reviews and meta-analyses published since the 2016 guidelines. Recommendations were organized by lines of treatment, which were informed by CANMAT-defined levels of evidence and supplemented by clinical support (consisting of expert consensus on safety, tolerability, and feasibility). Drafts were revised based on review by patient partners, expert peer review, and a defined expert consensus process.

resultsThe updated guidelines comprise eight primary topics, in a question-and-answer format, that map a patient care journey from assessment to selection of evidence-based treatments, prevention of recurrence, and strategies for inadequate response. The guidelines adopt a personalized care approach that emphasizes shared decision-making that reflects the values, preferences, and treatment history of the patient with MDD. Tables provide new and updated recommendations for psychological, pharmacological, lifestyle, complementary and alternative medicine, digital health, and neuromodulation treatments. Caveats and limitations of the evidence are highlighted.

conclusionsThe CANMAT 2023 updated guidelines provide evidence-informed recommendations for the management of MDD, in a clinician-friendly format. These updated guidelines emphasize a collaborative, personalized, and systematic management approach that will help optimize outcomes for adults with MDD.

Indexed as

Major Depressive DisorderAdultCanadaHumansMeta-Analysis as TopicSystematic Reviews as Topicadult psychiatryclinical practice guidelinesdepressive disorderselectroconvulsive therapyevidence-based medicinemajor depressive disorderpharmacotherapypsychotherapysystematic reviews

Identifiers

PMID38711351
PMCPMC11351064

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.