Evidence map›Paper›PMID 38711165›Full record

ArticleRNA biology2024

Truncating the spliceosomal 'rope protein' Prp45 results in Htz1 dependent phenotypes.

Kateřina Abrhámová, Martina Groušlová, Anna Valentová, Xinxin Hao, Beidong Liu, Martin Převorovský, Ondřej Gahura, František Půta, Per Sunnerhagen, Petr Folk

Abstract read
In one paragraph

Article in RNA biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kateřina AbrhámováDepartment of Cell Biology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID 0000-0002-6299-8641
Martina GroušlováDepartment of Cell Biology, Faculty of Science, Charles University, Praha, Czech Republic.
Anna ValentováDepartment of Cell Biology, Faculty of Science, Charles University, Praha, Czech Republic.
Xinxin HaoDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Beidong LiuDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Martin PřevorovskýDepartment of Cell Biology, Faculty of Science, Charles University, Praha, Czech Republic.
Ondřej GahuraInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice, Czech Republic.ORCID 0000-0002-2925-4763
František PůtaDepartment of Cell Biology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID 0000-0002-8313-878X
Per SunnerhagenDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-0967-8729
Petr FolkDepartment of Cell Biology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID 0000-0003-3813-7777

Funding

Charles University SVV260083, GAUK119710, GAUK441711, AND GAUK8214EMBO Short Term Fellowship ASTF 226-2005European Social Fund and the state budget of the Czech Republic CZ.1.07/2.3.00/30.0022Marie Curie Host fellowship QLK-CT2000-60036Swedish Cancer Fund 22-2014
6 · The paper itself

Abstract

Spliceosome assembly contributes an important but incompletely understood aspect of splicing regulation. Prp45 is a yeast splicing factor which runs as an extended fold through the spliceosome, and which may be important for bringing its components together. We performed a whole genome analysis of the genetic interaction network of the truncated allele of

Indexed as

IntronsPhenotypeRNA SplicingSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSpliceosomesGene Expression Regulation, FungalHistonesRNA Splicing FactorsHistonesRNA Splicing FactorsSaccharomyces cerevisiae Proteinschromatin modifiersco-transcriptional splicingH2A.Zspliceosome assemblySynthetic genetic array analysis

Identifiers

PMID38711165
PMCPMC11085953

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.