Evidence map›Paper›PMID 38711010›Full record

Trial reportBMC geriatrics2024

A feasibility study on preoperative carbohydrate loading in older patients undergoing hip fracture surgery.

Kai Sing Yap, P S Loh, Yi Xian Foong, Chu Zhen Mok, Terence Ong, Hui Min Khor

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04614181 (The Feasibility and Benefits of Pre-operative Whey-protein Infused Carbohydrate Loading in Elderly With Hip Fractures Undergoing Surgery), which is not on this map. Cited by 8 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04614181 nacompletednot on this map

The Feasibility and Benefits of Pre-operative Whey-protein Infused Carbohydrate Loading in Elderly With Hip Fractures Undergoing Surgery: a Pilot Study

TypeinterventionalSponsorUniversity of MalayaRan2020 to 2021Enrolled34ConditionsHip FracturesArmsNestle Resource drink, Usual care
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kai Sing YapDepartment of Anaesthesiology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
P S LohDepartment of Anaesthesiology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia. lohps@ummc.edu.my.
Yi Xian FoongDepartment of Anaesthesiology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Chu Zhen MokDepartment of Dietetics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.
Terence OngDepartment of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Hui Min KhorDepartment of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreoperative carbohydrate loading in Enhanced Recovery After Surgery is an independent predictor of postoperative outcomes. By reducing the impact of surgical stress response, fasting-induced insulin resistance is modulated. As a clear fluid, consuming carbohydrate drink is safe up to 2 h preoperatively. Widely practiced in abdominal surgeries, its implementation in hip fracture surgeries is yet to be recognized. This study aimed to identify the feasibility of preoperative carbohydrate loading in hip fracture surgery and assess its clinical effects.

methodsThis was a randomized controlled, open labelled trial. Patients ≥ 65 years old without diabetes mellitus, has hip fracture were recruited in a tertiary hospital between November 2020 and May 2021. The intervention was carbohydrate loading versus standard preoperative fasting.

resultsThirty-four ASA I-III patients (carbohydrate loading and control, n = 17 each), mean age 78 years (SEM ± 1.5), mean body mass index 23.7 (SEM ± 0.6 kg/m

conclusionThe implementation of preoperative carbohydrate loading was found to be feasible preoperatively in hip fracture surgeries but requires careful coordination among multidisciplinary teams. An adequately powered randomized controlled study is needed to examine the full benefits of preoperative carbohydrate loading in this group of patients.

trial registrationThis study was registered in ClinicalTrial.gov (ClinicalTrials.gov identifier: NCT04614181, date of registration: 03/11/2020).

Indexed as

Diet, Carbohydrate LoadingFeasibility StudiesHip FracturesPreoperative CareAgedAged, 80 and overEnhanced Recovery After SurgeryFastingFemaleHumansMaleCarbohydrate loadingElderlyHip fracture

Identifiers

PMID38711010
PMCPMC11075227

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.