ArticleJournal of neuroscience methods2024
CARLA: Adjusted common average referencing for cortico-cortical evoked potential data.
Article in Journal of neuroscience methods, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Methodologies to detect cortico-cortical evoked potentials: a systematic review.Frontiers in human neuroscience · 2025Pooled it
- Network reorganization of anterograde thalamic connectivity during non-periodic patterned deep brain stimulation.iScience · 2026Article
- Electrophysiological features of signals recorded from white matter.bioRxiv : the preprint server for biology · 2026Article
- Single pulse electrical stimulation in white matter modulates iEEG visual responses in human early visual cortex.PLoS computational biology · 2026Article
- Stimulation-evoked orbitofrontal activity as a biomarker for DBS personalization in depression.medRxiv : the preprint server for health sciences · 2026Article
- A practical preprocessing pipeline for concurrent TMS-iEEG: Critical steps and methodological considerations.NeuroImage · 2026Article
- Structural and effective brain connectivity in focal epilepsy.Neuroimage. Reports · 2025Article
- A Practical Preprocessing Pipeline for Concurrent TMS-iEEG: Critical Steps and Methodological Considerations.bioRxiv : the preprint server for biology · 2025Article
- Proper reference selection and re-referencing to mitigate bias in single pulse electrical stimulation data.Journal of neuroscience methods · 2025Article
- ER-detect: A pipeline for robust detection of early evoked responses in BIDS-iEEG electrical stimulation data.Journal of neuroscience methods · 2025Article
- ER-detect: a pipeline for robust detection of early evoked responses in BIDS-iEEG electrical stimulation data.bioRxiv : the preprint server for biology · 2024Article
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8 authors.
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Abstract
Human brain connectivity can be mapped by single pulse electrical stimulation during intracranial EEG measurements. The raw cortico-cortical evoked potentials (CCEP) are often contaminated by noise. Common average referencing (CAR) removes common noise and preserves response shapes but can introduce bias from responsive channels. We address this issue with an adjusted, adaptive CAR algorithm termed "CAR by Least Anticorrelation (CARLA)". CARLA was tested on simulated CCEP data and real CCEP data collected from four human participants. In CARLA, the channels are ordered by increasing mean cross-trial covariance, and iteratively added to the common average until anticorrelation between any single channel and all re-referenced channels reaches a minimum, as a measure of shared noise. We simulated CCEP data with true responses in 0-45 of 50 total channels. We quantified CARLA's error and found that it erroneously included 0 (median) truly responsive channels in the common average with ≤42 responsive channels, and erroneously excluded ≤2.5 (median) unresponsive channels at all responsiveness levels. On real CCEP data, signal quality was quantified with the mean R
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