Evidence map›Paper›PMID 38709991›Full record

ArticleJCO precision oncology2024

Are FGFR Fusions and Mutations the Next Tumor-Agnostic Targets in Oncology?

Haley Ellis, Lipika Goyal

Abstract readEditorialComment
PubMed Publisher
In one paragraph

Article in JCO precision oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Haley EllisDivision of Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Lipika GoyalStanford Cancer Center, Division of Oncology, Stanford School of Medicine, Palo Alto, CA.ORCID 0000-0002-9777-6221

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gong et al present two NCI-MATCH tumor-agnostic trials evaluating erdafitinib for FGFR-altered cancers, marking steppingstones in precision oncology.

Indexed as

MutationNeoplasmsQuinoxalinesReceptors, Fibroblast Growth FactorHumansPrecision MedicinePyrazoleserdafitinibPyrazolesQuinoxalinesReceptors, Fibroblast Growth Factor

Identifiers

PMID38709991

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.