Evidence map›Paper›PMID 38709456›Full record

ArticleJournal of thrombosis and thrombolysis2024

Intraoperative haemoadsorption for antithrombotic drug removal during cardiac surgery: initial report of the international safe and timely antithrombotic removal (STAR) registry.

Michael Schmoeckel, Matthias Thielmann, Kambiz Hassan, Stephan Geidel, Jan Schmitto, Anna L Meyer, Keti Vitanova, Andreas Liebold, Nandor Marczin, Martin H Bernardi and 6 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Journal of thrombosis and thrombolysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05077124 (Safe and Timely Antithrombotic Removal), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05077124 recruitingnot on this map

Safe and Timely Antithrombotic Removal (STAR) Registry: International Registry on the Use of CytoSorb for Removal of Antithrombotic Agents in the Acute Hospital Setting

TypeobservationalSponsorCytoSorbents, IncRan2021 to 2025Enrolled1,000ConditionsHemorrhage, Surgical, Hemorrhage Postoperative, Blood Loss, Surgical, Blood Loss, PostoperativeArmsCytoSorb
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Antibiotics and Other Drugs Removal by the CytoSorbAntibiotics (Basel, Switzerland) · 2026
    Review
  3. Potential Clinical Use of CytoSorbLife (Basel, Switzerland) · 2025
    Article
  4. 2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  5. Article
  6. Intraoperative Hemoadsorption in Heart Transplant Surgery: A 5-Year Experience.Journal of cardiovascular development and disease · 2025
    Article
  7. Article
  8. Observational
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Michael Schmoeckel *Department of Cardiac Surgery, Klinikum Grosshadern, Ludwig-Maximilians-University, Marchioninistr. 15, Munich, D-81377, Germany. michael.schmoeckel@med.uni-muenchen.de.
Matthias Thielmann *Department of Thoracic- and Cardiovascular Surgery, West German Heart and Vascular Center, Essen, Germany.
Kambiz HassanDepartment of Cardiac Surgery, Asklepios Klinik St. Georg, Hamburg, Germany.
Stephan GeidelDepartment of Cardiac Surgery, Asklepios Klinik St. Georg, Hamburg, Germany.
Jan SchmittoDepartment of Cardiac-, Thoracic-, Transplantation- and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Anna L MeyerDepartment of Cardiothoracic Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Keti VitanovaDepartment of Cardiovascular Surgery, German Heart Centre, Munich, Germany.
Andreas LieboldDepartment of Cardiothoracic and Vascular Surgery, Ulm University Medical Center, Ulm, Germany.
Nandor MarczinDepartment of Anaesthesia, Royal Brompton Hospital, Royal Brompton & Harefield Hospitals, Part of Guy's and St Thomas' NHS Foundation Trust, London, UK.
Martin H BernardiDivision of Cardiothoracic and Vascular Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Vienna, Austria.
Rene TandlerDepartment of Cardiac Surgery, University Hospital Erlangen, Erlangen, Germany.
Sandra LindstedtDepartment of Cardiothoracic Surgery and Transplantation, Skåne University Hospital, Lund, Sweden.
Marijana Matejic-SpasicCytoSorbents Europe GmbH, Berlin, Germany.
Daniel WendtDepartment of Thoracic- and Cardiovascular Surgery, West German Heart and Vascular Center, Essen, Germany.ORCID http://orcid.org/0009-0008-1074-7200
Efthymios N DeliargyrisCytoSorbents Inc, Princeton, NJ, USA.
Robert F StoreyDivision of Clinical Medicine, University of Sheffield, Sheffield, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraoperative antithrombotic drug removal by haemoadsorption is a novel strategy to reduce perioperative bleeding in patients on antithrombotic drugs undergoing cardiac surgery. The international STAR registry reports real-world clinical outcomes associated with this application. All patients underwent cardiac surgery before completing the recommended washout period. The haemoadsorption device was incorporated into the cardiopulmonary bypass (CPB) circuit. Patients on P2Y

Indexed as

Cardiac Surgical ProceduresFibrinolytic AgentsRegistriesAgedBlood Loss, SurgicalCardiopulmonary BypassFemaleHumansIntraoperative CareMaleMiddle AgedFibrinolytic AgentsAntithrombotic removalCardiac surgeryCytoSorbDOACHaemoadsorptionTicagrelor

Identifiers

PMID38709456
PMCPMC11315775

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.