Evidence map›Paper›PMID 38709168›Full record

ArticleJournal of the European Academy of Dermatology and Venereology : JEADV2025

Drug utilization among young adults with atopic dermatitis: Influence of sex, socio-economic status and disease severity.

P L Carmanius, S Lundin, M Ödling, E Kimland, N Ballardini, E Melén, A Bergström, E Dahlén

Abstract read
In one paragraph

Article in Journal of the European Academy of Dermatology and Venereology : JEADV, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

P L CarmaniusDepartment of Pharmacy, Faculty of Pharmacy, Uppsala University, Uppsala, Sweden.
S LundinDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-3193-4722
M ÖdlingDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
E KimlandThe Swedish Medical Products Agency, Uppsala, Sweden.
N BallardiniDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-6759-346X
E MelénDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
A BergströmInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
E DahlénDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-5502-2405

Funding

Astma- och AllergiförbundetForskningsrådet om Hälsa, Arbetsliv och Välfärd 2017-00526Hjärt-LungfondenRegion Stockholm (ALF project)Svenska Forskningsrådet Formas 2016-01646Thermo Fisher ScientificVetenskapsrådet 2016-03086Vetenskapsrådet 2018-02524Vetenskapsrådet 2020-02170
6 · The paper itself

Abstract

backgroundAtopic dermatitis (AD) affects individuals of all ages, and the first-line treatment are emollients and topical corticosteroids. There is insufficient knowledge about factors possibly affecting the drug utilization of young adults with AD.

objectivesTo describe the drug utilization of young adults with AD in relation to sex, socio-economic status and disease severity.

methodsA cross-sectional study based on the 24-year follow-up from the population-based BAMSE (Children, Allergy, Milieu, Stockholm, Epidemiology Survey) birth cohort linked with dispensing data from the National Drug Register (n = 2912). Self-reported AD and socio-economic status were defined from questionnaire data and disease severity was determined through the clinical examination and Patient-Oriented Eczema Measure questionnaire.

resultsThe prevalence of AD in young adults was 17.7% (n = 516) and 45.5% of them were dispensed at least one drug for the treatment of AD during the study period (January 2016 to June 2019). Topical corticosteroids (TCS) were the most common drugs (32.9%) followed by emollients (21.7%). A larger proportion of men were dispensed TCS than women (39.0% vs. 29.1%: p-value = 0.020). A larger proportion of young adults with moderate-to-severe AD were dispensed TCS than those with mild AD (52.6% vs. 35.3%: p-value = 0.026). No one was dispensed the recommended amount of emollients and less than five individuals were dispensed the recommended amount of TCS for mild disease. Male sex (adj.OR 1.54, 95% CI 1.06-2.34) and moderate-to-severe AD (adj.OR 2.62, 95% CI 1.59-4.31) were associated with dispensation of TCS.

conclusionsA large proportion of young adults with AD was undertreated or untreated. Sex and disease severity did affect the dispensing patterns of investigated drugs.

Indexed as

Dermatitis, AtopicSeverity of Illness IndexAdolescentAdrenal Cortex HormonesAdultCross-Sectional StudiesDrug UtilizationEmollientsFemaleHumansMaleSex FactorsSocial ClassSwedenYoung AdultAdrenal Cortex HormonesEmollients

Identifiers

PMID38709168
PMCPMC11664466

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.