Evidence map›Paper›PMID 38709058›Full record

ArticleMicrobiology spectrum2024

Microbroth dilution method for antibiotic susceptibility testing of fastidious and anaerobic bacteria of the urinary microbiome.

Wilson Geaman, Brian I Choi, Jacob Kaindl, Caroline Gonzalez, Alan J Wolfe

Abstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wilson GeamanDepartment of Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois, USA.
Brian I ChoiDepartment of Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois, USA.ORCID 0000-0001-5859-9050
Jacob KaindlDepartment of Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois, USA.
Caroline GonzalezDepartment of Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois, USA.
Alan J WolfeDepartment of Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois, USA.ORCID 0000-0003-4532-0545

Funding

Pathnostics
6 · The paper itself

Abstract

Bacterial isolates from the human urinary microbiome have been extensively studied for their antibiotic resistance; however, little work has been done on those isolates that are difficult to grow IMPORTANCE: Antibiotic susceptibilities of fastidious and anaerobic bacteria of the human urinary microbiome are largely underreported due to difficulty in growing them in the lab environment. The current standard medium, Muller-Hinton broth, has difficulty supporting the growth of many of these species, leaving microbiologists without a standardized method. To address this need, this study offers a methodology to survey susceptibilities in a high-throughput manner of these understudied microbes with a proposed harmonized medium, NYCIII, which is capable of supporting the growth of both fastidious and non-fastidious urinary microbes. Broader standardization of this method can allow for the development of antibiotic-resistant breakpoints of the many uncharacterized urinary microbes.

Indexed as

Anti-Bacterial AgentsBacteria, AnaerobicMicrobial Sensitivity TestsMicrobiotaBacteriaCulture MediaHumansUrinary Tract InfectionsUrineAnti-Bacterial AgentsCulture Mediaanaerobesantibiotic resistancefastidious isolateshuman microbiomemicrobiomesusceptibility testingurinary tract infection

Identifiers

PMID38709058
PMCPMC11237461

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.