Evidence map›Paper›PMID 38709005›Full record

ArticleAntimicrobial agents and chemotherapy2024

Koji Takemoto, Ryo Nakayama, Koichi Fujimoto, Yumiko Suzuki, Yukiko Takarabe, Masako Honsho, Sachiko Kitahara, Yoshihiko Noguchi, Hidehito Matsui, Tomoyasu Hirose and 4 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Membrane-Focused Strategies AgainstAntibiotics (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Koji TakemotoDrug Research Division, Sumitomo Pharma Co., Ltd., Osaka, Japan.ORCID 0009-0002-0894-8624
Ryo NakayamaDrug Research Division, Sumitomo Pharma Co., Ltd., Osaka, Japan.
Koichi FujimotoDrug Research Division, Sumitomo Pharma Co., Ltd., Osaka, Japan.
Yumiko SuzukiŌmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.
Yukiko TakarabeŌmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.
Masako HonshoŌmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.
Sachiko KitaharaDrug Research Division, Sumitomo Pharma Co., Ltd., Osaka, Japan.
Yoshihiko NoguchiŌmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.
Hidehito MatsuiŌmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.
Tomoyasu HiroseŌmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.
Yukihiro AsamiŌmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.
Jun HidakaDrug Research Division, Sumitomo Pharma Co., Ltd., Osaka, Japan.
Toshiaki SunazukaŌmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.
Hideaki HanakiŌmura Satoshi Memorial Institute, Kitasato University, Tokyo, Japan.

Funding

Japan Agency for Medical Research and Development (AMED) JP17pc0101002
6 · The paper itself

Abstract

KSP-1007 is a novel bicyclic boronate-based broad-spectrum β-lactamase inhibitor and is being developed in combination with meropenem (MEM) for the treatment of infections caused by carbapenem-resistant Gram-negative bacteria, a global health concern, and here, we describe its characteristics. KSP-1007 exhibited low apparent inhibition constant (

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsAzabicyclo Compoundsbeta-Lactamase Inhibitorsbeta-LactamasesMeropenemMicrobial Sensitivity TestsAnimalsBacterial ProteinsBoronic AcidsCarbapenem-Resistant EnterobacteriaceaeCarbapenemsCeftazidimeCephalosporinsColistinDrug CombinationsAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsBacterial Proteinsbeta-Lactamase Inhibitorsbeta-LactamasesBoronic AcidscarbapenemaseCarbapenemsCeftazidimeCephalosporinsColistinDrug CombinationsMeropenemrelebactamvaborbactamantibiotic resistancebeta-lactamasescarbapenems

Identifiers

PMID38709005
PMCPMC11620503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.