Evidence map›Paper›PMID 38708686›Full record

ArticleFuture medicinal chemistry2024

Synthesis and antiproliferative evaluation of novel 3,5,8-trisubstituted coumarins against breast cancer.

Manar G Salem, Alaa M Alqahtani, Suraj N Mali, Hussah Abdullah Alshwyeh, Rahul D Jawarkar, Abdulmalik S Altamimi, Samar Z Alshawwa, Ebtesam Al-Olayan, Essa M Saied, Mohamed F Youssef

Abstract read
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In one paragraph

Article in Future medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Manar G SalemPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt.
Alaa M AlqahtaniDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Umm Al-Qura University, Makkah, 21955, Saudi Arabia.
Suraj N MaliSchool of Pharmacy, DY Patil Deemed to be University Sector 7, Nerul, Navi Mumbai, 400706, India.
Hussah Abdullah AlshwyehDepartment of Biology, College of Science, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.
Rahul D JawarkarDepartment of Medicinal Chemistry & Drug Discovery, Dr. Rajendra Gode Institute of Pharmacy, University Mardi Road, Amravati, 444603, India.
Abdulmalik S AltamimiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, PO Box 173, Alkharj, 11942, Saudi Arabia.
Samar Z AlshawwaDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, PO Box 84428, Riyadh, 11671, Saudi Arabia.
Ebtesam Al-OlayanDepartment of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Essa M SaiedChemistry Department (Biochemistry Division), Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt.ORCID 0000-0002-7342-6200
Mohamed F YoussefChemistry Department (Organic Chemistry Division), Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsApoptosisBreast NeoplasmsCell ProliferationCoumarinsDrug Screening Assays, AntitumorCell CycleCell Line, TumorDNA Topoisomerases, Type IIErbB ReceptorsFemaleHumansMCF-7 CellsMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsCoumarinsDNA Topoisomerases, Type IIErbB Receptorsbreast cancercell cycle distributioncytotoxic activityflow cytometric analysismolecular dynamicsmolecular modelingprogrammed cell deathsubstituted coumarinstopoisomerase IIβ

Identifiers

PMID38708686
PMCPMC11216633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.