Evidence map›Paper›PMID 38708493›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2024

[Immunogenic and toxic effects of graphene oxide nanoparticles in mouse skeletal muscles and human red blood cells].

Yiming Sun, Ailan Huang, Zhi Zhao, Chen Song, Guihua Lai

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yiming SunDepartment of Human Anatomy, Bengbu Medical University, Bengbu 233030, China.
Ailan HuangDepartment of Food Quality and Safety, Bengbu Medical University, Bengbu 233030, China.
Zhi ZhaoDepartment of Orthopedics of First Affiliated Hospital, Bengbu Medical University, Bengbu 233030, China.
Chen SongDepartment of Anatomy, Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, Southern Medical University, Guangzhou 510515, China.
Guihua LaiDepartment of Human Anatomy, Bengbu Medical University, Bengbu 233030, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate immunogenic and toxic effects of graphene oxide (GO) nanoparticles in mouse skeletal muscles and in human blood

methodsGO nanoparticles prepared using a probe sonicator were supended in deionized H

resultsGO nanoparticles suspended in PBS exhibited better colloidal dispersity, stability and surface charge effects than those in deionized H

conclusionGO nanoparticles can induce sustained inflammatory and immunological responses in mouse GNs and cause RBC hemolysis and blood coagulation impairment, suggesting its muscular toxicity and hematotoxicity at high concentrations.

Indexed as

ErythrocytesGraphiteHemolysisMice, Inbred C57BLMuscle, SkeletalNanoparticlesAnimalsBlood CoagulationHumansMiceParticle Sizegraphene oxideGraphitegraphene oxidehematotoxicityimmune responsemuscular toxicity

Identifiers

PMID38708493
PMCPMC11073950

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.