Evidence map›Paper›PMID 38708416›Full record

ReviewEngineering in life sciences2024

Gut microbiota and childhood malnutrition: Understanding the link and exploring therapeutic interventions.

Sevda Zoghi, Fatemah Sadeghpour Heravi, Zeinab Nikniaz, Masoud Shirmohamadi, Seyed Yaghoub Moaddab, Hamed Ebrahimzadeh Leylabadlo

Abstract readReview
In one paragraph

Review in Engineering in life sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sevda ZoghiLiver and Gastrointestinal Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran.
Fatemah Sadeghpour HeraviMacquarie Medical School Macquarie University Sydney Australia.
Zeinab NikniazLiver and Gastrointestinal Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran.
Masoud ShirmohamadiLiver and Gastrointestinal Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran.
Seyed Yaghoub MoaddabLiver and Gastrointestinal Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran.
Hamed Ebrahimzadeh LeylabadloLiver and Gastrointestinal Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood malnutrition is a metabolic condition that affects the physical and mental well-being of children and leads to resultant disorders in maturity. The development of childhood malnutrition is influenced by a number of physiological and environmental factors including metabolic stress, infections, diet, genetic variables, and gut microbiota. The imbalanced gut microbiota is one of the main environmental risk factors that significantly influence host physiology and childhood malnutrition progression. In this review, we have evaluated the gut microbiota association with undernutrition and overnutrition in children, and then the quantitative and qualitative significance of gut dysbiosis in order to reveal the impact of gut microbiota modification using probiotics, prebiotics, synbiotics, postbiotics, fecal microbiota transplantation, and engineering biology methods as new therapeutic challenges in the management of disturbed energy homeostasis. Understanding the host-microbiota interaction and the remote regulation of other organs and pathways by gut microbiota can improve the effectiveness of new therapeutic approaches and mitigate the negative consequences of childhood malnutrition.

Indexed as

dysbiosisgut microbiotamalnourished childrenovernutritionundernutrition

Identifiers

PMID38708416
PMCPMC11065333

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.