Evidence map›Paper›PMID 38708345›Full record

ArticlePeerJ2024

Cystatin C: immunoregulation role in macrophages infected with

Blanca Esther Blancas-Luciano, Ingeborg Becker-Fauser, Jaime Zamora-Chimal, Luis Jiménez-García, Reyna Lara-Martínez, Armando Pérez-Torres, Margarita González Del Pliego, Elsa Liliana Aguirre-Benítez, Ana María Fernández-Presas

Abstract read
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Blanca Esther Blancas-LucianoPosgrado en Ciencias Biológicas, Unidad de Posgrado, Circuito de Posgrados, Ciudad Universitaria, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.
Ingeborg Becker-FauserUnidad de Investigación en Medicina Experimental, Hospital General de México, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Jaime Zamora-ChimalUnidad de Investigación en Medicina Experimental, Hospital General de México, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Luis Jiménez-GarcíaDepartamento de Biología Celular. Facultad de Ciencias, Ciudad Universitaria, Universidad Nacional Autónoma de México, Ciudad de México, México.
Reyna Lara-MartínezDepartamento de Biología Celular. Facultad de Ciencias, Ciudad Universitaria, Universidad Nacional Autónoma de México, Ciudad de México, México.
Armando Pérez-TorresDepartamento de Biología Celular y Tisular, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Margarita González Del PliegoDepartamento de Embriología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.
Elsa Liliana Aguirre-BenítezDepartamento de Embriología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.
Ana María Fernández-PresasDepartamento de Microbiología y Parasitologia, Facultad de Medicina, Ciudad Universitaria, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.

Funding

CONAHCYTDGAPAPAPITTUNAM
6 · The paper itself

Abstract

Background: Periodontitis is a chronic infectious disease, characterized by an exacerbated inflammatory response and a progressive loss of the supporting tissues of the teeth. Methods: Monocyte-derived macrophages generated from peripheral blood were infected with Results: Our results showed that cystatin C inhibits the extracellular growth of Conclusions: Cystatin C has antimicrobial and immuno-regulatory activity in macrophages infected with

Indexed as

Cystatin CMacrophagesNitric OxidePorphyromonas gingivalisReactive Oxygen SpeciesApoptosisCytokinesHumansPeriodontitisCystatin CCytokinesNitric OxideReactive Oxygen SpeciesCystatin CMacrophageOral peptidePorphyromonas gingivalis

Identifiers

PMID38708345
PMCPMC11067906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.