Evidence map›Paper›PMID 38708148›Full record

ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2024

Role of Interphase FISH Assay on Air-Dried Smears in Identifying Specific Structural Chromosomal Abnormalities among Pediatric Patients with Acute Leukemias.

Karthik Bommannan, Jhansi Rani Arumugam, Teena Koshy, Venkatraman Radhakrishnan, Shirley Sundersingh

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Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Karthik BommannanDepartment of Oncopathology, Cancer Institute (W.I.A.), Chennai, 600020 India.ORCID 0000-0003-0851-886X
Jhansi Rani ArumugamDepartment of Oncopathology, Cancer Institute (W.I.A.), Chennai, 600020 India.
Teena KoshyDepartment of Oncopathology, Cancer Institute (W.I.A.), Chennai, 600020 India.
Venkatraman RadhakrishnanDepartment of Medical Oncology, Cancer Institute (W.I.A.), Chennai, 600020 India.
Shirley SundersinghDepartment of Oncopathology, Cancer Institute (W.I.A.), Chennai, 600020 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukemia-associated structural chromosomal abnormalities (SCA) can be identified either by karyotyping or interphase-fluorescence in-situ hybridization (i-FISH) assays. Both karyotyping and i-FISH on mononuclear cell suspension are time, resource, and manpower-consuming assays. In this study, we have compared the results of specific leukemia-associated SCAs identified by i-FISH on air-dried bone marrow (BM)/peripheral blood (PB) smears and BM karyotyping. The study was conducted among pediatric patients (age ≤ 18 years) diagnosed with acute leukemias between January 2018 to December 2022. The results of i-FISH on air-dried BM/PB smears and BM-karyotyping for our SCA of interest ( Supplementary Information: The online version contains supplementary material available at 10.1007/s12288-023-01699-2.

Indexed as

FISHKaryotypingLeukemiaPediatricSmears

Identifiers

PMID38708148
PMCPMC11065818

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