Evidence map›Paper›PMID 38707880›Full record

ArticleJournal of obstetrics and gynaecology of India2024

Evaluation of CRP/Albumin Ratio in Polycystic Ovarian Syndrome.

Nandini Upadhyay, Edelbert Anthonio Almeida, Alpana Singh, S V Madhu, Dinesh Puri, Mohit Mehndiratta

Abstract read
In one paragraph

Article in Journal of obstetrics and gynaecology of India, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nandini UpadhyayThird Year Part 1, UCMS & GTBH, University of Delhi, New Delhi, India.
Edelbert Anthonio AlmeidaDepartment of Biochemistry, UCMS & GTBH, University of Delhi, New Delhi, India.
Alpana SinghDepartment of Obstetrics and Gynaecology, University College of Medical Sciences and GTB Hospital (UCMS & GTBH), University of Delhi, Dilshad Garden, New Delhi, 110095 India.
S V MadhuDepartment of Endocrinology, UCMS & GTBH, University of Delhi, New Delhi, India.
Dinesh PuriDepartment of Biochemistry, UCMS & GTBH, University of Delhi, New Delhi, India.
Mohit MehndirattaDepartment of Biochemistry, UCMS & GTBH, University of Delhi, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Polycystic ovarian syndrome is a common endocrine disorder among women of reproductive age. It is characterized by menstrual abnormalities, hyperandrogenism and polycystic ovaries and can lead to many complications. Studies have postulated the role of inflammation in the pathophysiology of PCOS. As acute phase reactants often serve as markers of inflammation, this study aimed to evaluate the role of inflammatory markers in women with PCOS and healthy controls. Material and Methods: A total of 60 participants were enrolled; 30 cases of PCOS and 30 age matched healthy controls. Peripheral venous blood was collected for assessment of CRP, serum albumin, serum total testosterone, serum fasting insulin and fasting blood glucose, following which statistical analysis was done. Results: The CRP/albumin ratio was found to be significantly higher in women with PCOS as compared to healthy controls along with serum total testosterone and HOMA-IR. Correlation between CRP/albumin ratio and the levels of serum total testosterone and insulin resistance was found to be non-significant. Conclusion: An elevated CRP/albumin ratio in cases of PCOS compared to healthy controls supports the hypothesis of inflammation playing a key role in the pathophysiology of PCOS. CRP/albumin ratio can serve as a cheaper biochemical marker of the disease subject to further validation studies to establish its use in Indian population.

Indexed as

Acute phase reactantsCRP/albuminInflammationPCOS

Identifiers

PMID38707880
PMCPMC11065824

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