Evidence map›Paper›PMID 38707777›Full record

ReviewRevista panamericana de salud publica = Pan American journal of public health2024

The importance of basic and translational research in caring for children with malignant solid tumors in Latin America.

María Belen Cancela, Milagros Dinardi, Rosario Aschero, Santiago Zugbi, Guillermo Chantada, Lorena Baroni, Paula Schaiquevich

Abstract readReview
In one paragraph

Review in Revista panamericana de salud publica = Pan American journal of public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

María Belen CancelaUnidad de Tratamientos Innovadores Hospital de Pediatría JP Garrahan Buenos Aires Argentina Unidad de Tratamientos Innovadores, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina.
Milagros DinardiUnidad de Tratamientos Innovadores Hospital de Pediatría JP Garrahan Buenos Aires Argentina Unidad de Tratamientos Innovadores, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina.
Rosario AscheroPediatric Cancer Center Barcelona Hospital Sant Joan de Deu Barcelona Spain Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu, Barcelona, Spain.
Santiago ZugbiUnidad de Tratamientos Innovadores Hospital de Pediatría JP Garrahan Buenos Aires Argentina Unidad de Tratamientos Innovadores, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina.
Guillermo ChantadaPediatric Cancer Center Barcelona Hospital Sant Joan de Deu Barcelona Spain Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu, Barcelona, Spain.
Lorena BaroniServicio de Hematología-Oncología Hospital de Pediatría JP Garrahan Buenos Aires Argentina Servicio de Hematología-Oncología, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina.
Paula SchaiquevichUnidad de Tratamientos Innovadores Hospital de Pediatría JP Garrahan Buenos Aires Argentina Unidad de Tratamientos Innovadores, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Basic and translational research in pediatric cancer are essential to improve patient care. To critically assess the developments achieved in these areas in Latin America, we systematically reviewed information published between 2013 and 2023. Methods: Studies of basic and translational research performed by investigators in Latin America evaluating pediatric malignant solid and central nervous system tumors were retrieved from PubMed. Original articles published in English between 2013 and 2023 were included. Collaborations among Latin American authors or among Latin American authors working with researchers from other continents were also included. Studies were excluded if they focused only on adults or on basic research in tumor biology not specifically related to the tumor types analyzed in this review. Results: A total of 550 articles were retrieved, but after removal of duplicates, 514 articles were included in the analysis, the majority of which were authored by researchers affiliated with institutions in Argentina, Brazil and Mexico. These countries also had the highest number of collaborations on original articles published with authors from Europe and North America. Argentina had the highest number of collaborations on original publications, with coauthors from Brazil and Uruguay. The median impact factor of the 244 journals in which articles were published was 3.5. The most commonly studied tumors were osteosarcomas, neuroblastomas and medulloblastomas; the most commonly studied areas were molecular analysis, tumor cell biology and biomarkers. Conclusions: In Latin America, research in pediatric oncology is on the agenda, despite a notable disparity in publication rates and frequency of collaboration between countries. There is a need to strengthen scientific collaboration within Latin America and with countries from other continents to promote research and to develop novel treatment strategies that reflect the local needs of children in Latin America who have solid tumors and brain cancer.

Indexed as

basic researchbrain neoplasmsLatin AmericaMalignant neoplasmstranslational research, biomedical

Identifiers

PMID38707777
PMCPMC11069327

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.