Evidence map›Paper›PMID 38707734›Full record

ArticleCancer diagnosis & prognosis

Radiological Cutoff Values for Diagnosis of Lymph Node Metastasis in Colorectal Cancer With Multilevel Analysis.

Yukitoshi Todate, Toshihiko Takada, Michitaka Honda, Teppei Miyakawa, Ryuya Yamamoto, Satoshi Toshiyama, Eiichi Nakao, Ryutaro Mashiko, Hirohito Kakinuma, Hidetaka Kawamura and 3 more

Abstract read
In one paragraph

Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yukitoshi TodateDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Toshihiko TakadaDepartment of General Medicine, Shirakawa Satellite for Teaching and Research, Fukushima Medical University, Fukushima, Japan.
Michitaka HondaDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Teppei MiyakawaDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Ryuya YamamotoDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Satoshi ToshiyamaDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Eiichi NakaoDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Ryutaro MashikoDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Hirohito KakinumaDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Hidetaka KawamuraDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Hisashi YamaguchiDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Yoshiaki TakagawaDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Koji KonoDepartment of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aim: A cutoff value for lymph node diameter in colorectal cancer lymph node metastases has not been established. This prospective study aimed to investigate the direct association between swollen lymph nodes identified on preoperative computed tomography (CT) and pathological findings and proposed a cutoff value. Patients and Methods: We enrolled patients scheduled to undergo curative surgery with lymph node dissection for colorectal adenocarcinoma who underwent preoperative contrast-enhanced CT and had swollen lymph nodes ≥7 mm in diameter. Two gastrointestinal surgeons intraoperatively identified the target lymph nodes to assess the association between lymph node diameter and pathological findings. The diagnostic performance for lymph node metastasis was determined using multi-level logistic modelling. Results: A total of 109 patients were enrolled, and 225 swollen lymph nodes were pathologically evaluated. Using a cutoff value of ≥9 mm for the short diameter, the positive and negative predictive values, sensitivity, and specificity were 100.0% (99.6%-100.0%), 99.9% (99.1%-100.0%), 62.0% (45.6%-76.0%), and 84.9% (67.0%-94.0%), respectively. Conclusion: The cutoff value for improving the positive predictive value for the preoperative lymph node metastasis diagnosis in colorectal cancer patients should be at least 9 mm in diameter.

Indexed as

Colorectal cancercomputed tomographylymph node metastasispredictive value of tests

Identifiers

PMID38707734
PMCPMC11062160

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